| 产品描述: | Bismuth Subsalicylate 是一种有效的口服抗酸和止泻试剂 (anti-diarrheal agent)。Bismuth Subsalicylate 通过抑制体内前列腺素合成 (prostaglandin synthesis),降低胃和肠道黏膜炎症。Bismuth Subsalicylate 广泛用于腹泻疾病的研究,包括消化不良、腹泻、恶心等。 |
| 体内研究: |
In the gastrointestinal tract, Bismuth Subsalicylate can be converted to salicylic acid and insoluble bismuth salts. Salicylic acid reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H synthase 1/2.Bismuth Subsalicylate (oral gavage; 100 mg/kg-350 mg/kg) significantly decreases castor oil-induced movement of a charcoal test meal along the small intestine of the mouse and rat and also decreases both the fecal output (dry or wet weight) and the frequency of diarrhea in mice. |
| 溶解性: |
DMSO : 1 mg/mL (2.76 mM; Need ultrasonic)
H2O : 0.1 mg/mL (0.28 mM; Need ultrasonic) |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.762 ml |
13.809 ml |
27.617 ml |
| 5 mM |
0.552 ml |
2.762 ml |
5.523 ml |
| 10 mM |
0.276 ml |
1.381 ml |
2.762 ml |
| 50 mM |
0.055 ml |
0.276 ml |
0.552 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |