氯胺T 三水合物

10mM in DMSO

Chloramine T trihydrate

SDS 产品使用指南

品牌：源叶(MedMol)

产品编号：V50422 一键复制产品信息

CAS号：7080-50-4

分子式：C₇H₇ClNNaO₂S·3H₂O

分子量：281.64

MDL：MFCD00000522

别名：N-氯-4-甲苯磺酰胺钠盐;对甲苯磺酰氯胺钠;氯氨基甲苯砜钠;氯亚明T

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V50422-1ml	10mM in DMSO	￥90.00 V50422-1ml ￥90.00 3-5天	0 货期：3-5天	-	-	-	-

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产品介绍参考文献(1篇) 质检证书(COA) 摩尔浓度计算器相关产品

产品描述：

容量分析中用作碘和次氯酸盐标准溶液的代用品。检定溴酸盐和卤素。测定碘化物、铊和锡。

体内研究：

A dose-dependently significant DNA damage in the rat tissues and inflammation is histopathologically noted around the terminal airways of the lung in both male and female rats. The 24-h exposure to 50 mg/L of chloramine-T is toxic for crayfish and leads to substantial loss of energy that became apparent during subsequently conducted physical stress. Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites. The activities of CYP2E1, CYP1A1/2 CYP2B1/2, CYP3A4 and CYP4A1/2 enzymes significantly increase after treatment with 2.50, 5 and 10 mg/kg bw/day tosylchloramide, in a dose-dependent manner. This effect is not observed after tosylchloramide treatment at dose of 1.25 mg/kg bw/day.

参考文献：

1. Kloth LC, et al. Bactericidal and cytotoxic effects of chloramine-T on wound pathogens and human fibroblasts in vitro. Adv Skin Wound Care. 2007 Jun;20(6):331-45.
2. Shim I, et al. Inhalation exposure to chloramine T induces DNA damage and inflammation in lung of Sprague-Dawley rats. J Toxicol Sci. 2013;38(6):937-46.
3. Kuklina I, et al. Investigation of chloramine-T impact on crayfish Astacus leptodactylus (Esch., 1823) cardiac activity. Environ Sci Pollut Res Int. 2014 Sep;21(17):10262-9.
4. Martínez MA, et al. Induction of cytochrome P450-dependent mixed function oxidase activities and peroxisome proliferation by chloramine-T in male rat liver. Food Chem Toxicol. 2017 Aug;106(Pt A):86-91.

溶解性：

溶于水，几乎不溶于苯、氯仿和乙醚。

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.551 ml	17.753 ml	35.506 ml
5 mM	0.71 ml	3.551 ml	7.101 ml
10 mM	0.355 ml	1.775 ml	3.551 ml
50 mM	0.071 ml	0.355 ml	0.71 ml