| 产品描述: | Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. |
| 靶点: |
Parasite |
| 体内研究: |
In an in vivo investigation, female mice are treated with Fluensulfone (or isoniazid as a positive control) for 3 and 7 days. Quantification of the cell proliferation by manual counting of BrdU-positive and BrdU-negative cells in the bronchiolar epithelium reveals an approximately fourfold increase of cell proliferation upon treatment with Fluensulfone and the positive control isoniazid compare with control. Increased cell proliferation is observed at 3 days but have reverted to the control level at day 7 |
| 参考文献: |
1. Kearn J, et al. Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones. Pestic Biochem Physiol. 2014 Feb;109:44-57. 2. Strupp C, et al. Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework. Toxicol Sci. 2012 Jul;128(1):284-94. |
| 溶解性: |
Soluble in DMSO、H2O |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.428 ml |
17.141 ml |
34.282 ml |
| 5 mM |
0.686 ml |
3.428 ml |
6.856 ml |
| 10 mM |
0.343 ml |
1.714 ml |
3.428 ml |
| 50 mM |
0.069 ml |
0.343 ml |
0.686 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |