| 产品描述： | RKI-1313 is a ROCK inhibitor with IC50s of 34, 8 µM for ROCK 1 and ROCK 2, respectively. RKI-1313 shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion or anchorage-independent growth |
| 靶点： |
ROCK1:34 μM (IC50);ROCK2:8 μM (IC50);ROCK |
| 参考文献： |
1. Patel RA, et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012 Oct 1;72(19):5025-34. |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.938 ml |
14.689 ml |
29.377 ml |
| 5 mM |
0.588 ml |
2.938 ml |
5.875 ml |
| 10 mM |
0.294 ml |
1.469 ml |
2.938 ml |
| 50 mM |
0.059 ml |
0.294 ml |
0.588 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京