| 产品描述: | NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway |
| 靶点: |
ZIP7 |
| 体外研究: |
NVS-ZP7-4 increases ER zinc levels, suggesting functional modulation of ZIP7 |
| 参考文献: |
1. Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb;15(2):179-188. |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
1.994 ml |
9.968 ml |
19.935 ml |
| 5 mM |
0.399 ml |
1.994 ml |
3.987 ml |
| 10 mM |
0.199 ml |
0.997 ml |
1.994 ml |
| 50 mM |
0.04 ml |
0.199 ml |
0.399 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |