品牌：源叶(MedMol)

产品编号：V52411 一键复制产品信息

CAS号：13095-47-1

分子式：C₅H₈O₅

分子量：148.11

别名：R-2-羟基戊二酸;2-hydroxypentanedioic acid;D-2-Hydroxyglutaric acid;R-2-HYDROXYGLUTARATE;(R)-2-Hydroxyglutaric acid;(R)-alpha-Hydroxyglutaric acid;D-alpha-Hydroxyglutaric acid

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V52411-1ml	10mM in DMSO	￥500.00 V52411-1ml ￥500.00 3-5天	0 货期：3-5天	-	-	-	-

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体内研究：

D-α-Hydroxyglutaric acid strongly inhibits glucose utilization, CO2 production and the respiratory chain in rat cerebral cortex and human skeletal muscle, as well as in submitochondrial particles from bovine heart, suggesting an impairment of the aerobic metabolism.
D-α-Hydroxyglutaric acid has also been proposed as an endogenous excitotoxic organic acid because it significantly decreased cell viability in neuronal cultures from chick embryo telencephalons and from neonatal rat hippocampus through stimulation of specific NMDA glutamate receptors.
D-α-Hydroxyglutaric acid (0.01-1 mM) significantly increases chemiluminescence and thiobarbituric acid-reactive substances (TBA-RS) and decreased total antioxidant reactivity (TAR) values in the cortical supernatants in 30-day-old-rats.

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	6.752 ml	33.759 ml	67.517 ml
5 mM	1.35 ml	6.752 ml	13.503 ml
10 mM	0.675 ml	3.376 ml	6.752 ml
50 mM	0.135 ml	0.675 ml	1.35 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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