Ki: 0.59 μM (reuptake of glutamate);IC50: 0.56 μM (Glycine B coagonist site of NMDA receptor)
体内研究:
Male Sprague-Dawley rats pretreated with 7-Chlorokynurenic acid (10 nM) shows a significant retardation of development of both the electroencephalographic and motor (17.7±2.9 daily stimulations) components of the seizure response.