| 产品描述: | PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors. in vivo binding experiments, in which PK 14105 was injected into rats with unilaterally lesioned striata, demonstrate that PK 14105 rapidly crosses the blood-brain-barrier and that there is a marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis[1]. It can also inhibit receptor ligands, calcium channel ligands and co-transporter in all salivary glands |
| 靶点: |
Others |
| 参考文献: |
1. Pascali C et al. The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites. Int J Rad Appl Instrum A. 1990;41(5):477-82. 2. Franklin C. Wong et al. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations. Biomed Res Int. 2013, 503095. |
| 溶解性: |
soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.622 ml |
13.11 ml |
26.219 ml |
| 5 mM |
0.524 ml |
2.622 ml |
5.244 ml |
| 10 mM |
0.262 ml |
1.311 ml |
2.622 ml |
| 50 mM |
0.052 ml |
0.262 ml |
0.524 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |