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WWL113

    
10mM in DMSO

WWL113

源叶(MedMol)
V53565 一键复制产品信息
947669-86-5
C29H26N2O4
466.52774
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
V53565-1ml
10mM in DMSO

¥820.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
靶点: IC50: 120 nM (Ces3), 100 nM (Ces1f).
体内研究: WWL113 (30 mg/kg, orally once a day) results in major improvement of multiple features of metabolic syndrome and ameliorated obesity-diabetes in mice with lowered levels of nonesterified free fatty acids (NEFAs), triglycerides (TGs), total cholesterol and fasted glucose as well as enhanced glucose tolerance.
WWL113 ameliorates obesity-diabetes in mice.
参考文献: 1. Dominguez, E., Galmozzi, A., Chang, J.W., et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat. Chem. Biol. 10(2), 113-121 (2014).
2. Galmozzi, et al. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Rep. 2014 Dec 11;9(5):1584-1593.
3. Turcotte C, et al. The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors. J Immunol. 2017 Apr 15;198(8):3255-3263.
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.143 ml 10.717 ml 21.435 ml
5 mM 0.429 ml 2.143 ml 4.287 ml
10 mM 0.214 ml 1.072 ml 2.143 ml
50 mM 0.043 ml 0.214 ml 0.429 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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