| 体内研究: |
Diphenylcyclopropenone (1.0 或 0.1% (w/v),暴露于双耳背侧,每天一次,连续 3 天,然后每周两次,连续 8 周) 增加小鼠平均耳厚,调节 B 细胞和 T 细胞的活化,增加小鼠胰腺淋巴结 IFN-γ-阳性 CD8+细胞的比例。 |
| 参考文献: |
1. Yugang Gong, et al. Diphenylcyclopropenone plays an effective therapeutic role by up-regulating the TSLP/OX40L/IL-13 pathway in severe alopecia areata. Exp Dermatol. 2021 Feb;30(2):278-283. 2. Zekayi Kutlubay, et al. Assessment of treatment efficacy of diphenylcyclopropenone (DPCP) for alopecia areata. Turk J Med Sci. 2020 Dec 17;50(8):1817-1824. 3. Hirota M, et al. Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone. J Toxicol Sci. 2010 Dec;35(6):871-9. 4. Svalgaard JD, et al. Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunol Res. 2014 Jan;58(1):40-50. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
4.849 ml |
24.244 ml |
48.487 ml |
| 5 mM |
0.97 ml |
4.849 ml |
9.697 ml |
| 10 mM |
0.485 ml |
2.424 ml |
4.849 ml |
| 50 mM |
0.097 ml |
0.485 ml |
0.97 ml |
|
| 注意: |
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