TPPS4 shows the highest tumor to tissue ratios after 96 hours injection with a dose dependent manner. TPPS4 appears to be cleared through the kidneys and absolute concentrations there are reduced with increasing time after injection.
参考文献:
1. Austen JD, et al. Intracellular localization of meso-Tetra(p-sulfophenyl)porphine: a potential tumor localizing agent. Cancer Treat Rep. 1978 Apr;62(4):511-8.