| 产品描述： | (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons |
| 靶点： |
group I/group II mGluR;GluR |
| 体内研究： |
(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons. Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent |
| 参考文献： |
1. Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. PLoS One, 2015 Sep 21, 10(9):e0138215. 2. Fiona Yeuk-Lun Choi, et al. The effects of (RS)-MCPG on amphetamine-induced sensitization in neonatal rats. |
| 溶解性： |
Soluble in DMSO、1M NaOH |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
4.78 ml |
23.901 ml |
47.801 ml |
| 5 mM |
0.956 ml |
4.78 ml |
9.56 ml |
| 10 mM |
0.478 ml |
2.39 ml |
4.78 ml |
| 50 mM |
0.096 ml |
0.478 ml |
0.956 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京