| 产品描述: | NSC23925 is a novel, selective and effective P-glycoprotein (Pgp) inhibitor. |
| 靶点: |
P-glycoprotein;Nrf2 |
| 体内研究: |
Both saline alone and NSC23925 alone treated tumors grow progressively. The usage of NSC23925 in paclitaxel chemotherapy significantly prolongs anticancer efficacy of paclitaxel |
| 参考文献: |
1. Yang X, et al. Nsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis. Int J Cancer. 2015 Oct 15;137(8):2029-39. 2. Duan Z, et al. NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistance. PLoS One. 2009 Oct 12;4(10):e7415. |
| 溶解性: |
Soluble in DMSO、H2O |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.87 ml |
14.35 ml |
28.699 ml |
| 5 mM |
0.574 ml |
2.87 ml |
5.74 ml |
| 10 mM |
0.287 ml |
1.435 ml |
2.87 ml |
| 50 mM |
0.057 ml |
0.287 ml |
0.574 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |