| 体内研究: |
1,2-Cyclohexylenedinitrilotetraacetic acid (36 mg/kg, ip, once a day for two days) 可在 Sprague-Dawley 大鼠模型中减轻锰引起的急性神经毒性。 |
| 参考文献: |
1. Tandon SK, et al. Removal of manganese by chelating agents from brain and liver of manganese treated rats: as in vitro and an in vivo study. Toxicology. 1975 Nov;5(2):237-41. 2. Sun Y, et al., Synthesis and characterization of racemic mixture and meso isomers of bis(trans-2-aminocyclohexyl)aminepentaacetic acid and the stabilities of their Gd(III) complexes. Inorg Chem. 2000 Apr 3;39(7):1480-6. 3. Hazell AS, et al., Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment. Neurosci Lett. 2006 Apr 3;396(3):167-71. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.887 ml |
14.437 ml |
28.874 ml |
| 5 mM |
0.577 ml |
2.887 ml |
5.775 ml |
| 10 mM |
0.289 ml |
1.444 ml |
2.887 ml |
| 50 mM |
0.058 ml |
0.289 ml |
0.577 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |