| 产品描述： | GNE-0439 is a novel Nav1.7-selective inhibitor with IC50 of 0.34 uM and inhibits Nav1.5 with an IC50 of 38.3 μM. GNE-0439 inhibits mutant N1742K channels (IC50=0.37 uM) in membrane potential assays. GNE-0439 possesses a carboxylic acid group, binds outside of the channel pore, and is unique compared with known selective VSD4 binders. |
| 保存条件： |
-80°C 12个月; -20°C 6个月, 干燥 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.895 ml |
14.473 ml |
28.945 ml |
| 5 mM |
0.579 ml |
2.895 ml |
5.789 ml |
| 10 mM |
0.289 ml |
1.447 ml |
2.895 ml |
| 50 mM |
0.058 ml |
0.289 ml |
0.579 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京