| 产品描述： | MT-1207 is an orally active and selective adrenergic α1 and 5-HT2A receptor antagonist. MT-1207 shows IC50<0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α1A, α1B, α1D and 5-HT2A, respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research. |
| 靶点： |
5-HT2A Receptor;α1A-adrenergic receptor:0.1 nM (IC50); α1B-adrenergic receptor:0.15 nM (IC50); α1B-adrenergic receptor:1.40 nM (Ki) |
| 保存条件： |
-80°C 6个月; -20°C 1个月,氮气保存 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.331 ml |
11.656 ml |
23.311 ml |
| 5 mM |
0.466 ml |
2.331 ml |
4.662 ml |
| 10 mM |
0.233 ml |
1.166 ml |
2.331 ml |
| 50 mM |
0.047 ml |
0.233 ml |
0.466 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京