| 产品描述： | UNC9995 is a β-arrestin2-biased agonist of dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thus prevents neuronal degeneration. Futhermore, UNC9995 activates the Drd2/β-arrestin2 signaling to prevent inflammation-related genes transcription-induced by JAK/STAT3. UNC9995 improves depressive behavior in mouse model, and improves astrocytes dysfunctions. |
| 体内研究： |
Mouse TREM-1 SCHOOL peptide 减少 J774 细胞中炎症细胞因子的产生。 |
| 保存条件： |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.851 ml |
19.254 ml |
38.507 ml |
| 5 mM |
0.77 ml |
3.851 ml |
7.701 ml |
| 10 mM |
0.385 ml |
1.925 ml |
3.851 ml |
| 50 mM |
0.077 ml |
0.385 ml |
0.77 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京