| 产品描述： | BTK inhibitor 10 is a potent and orally active Bruton kinase (BTK) inhibitor, extracted from patent WO2018145525, example 33. BTK inhibitor 10 has a potential for rheumatoid arthritis treatment. |
| 体外研究： |
BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33[1]. |
| 保存条件： |
-80°C 12个月; -20°C 6个月,干燥, 避光 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.265 ml |
11.326 ml |
22.651 ml |
| 5 mM |
0.453 ml |
2.265 ml |
4.53 ml |
| 10 mM |
0.227 ml |
1.133 ml |
2.265 ml |
| 50 mM |
0.045 ml |
0.227 ml |
0.453 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
