| 产品描述： | WB436B is a highly selective STAT3 inhibitor. WB436B can selectively inhibit STAT3-Tyr705 phosphorylation and the expression of STAT3 target genes, showing cytotoxic effects on pancreatic cancer cells and inducing apoptosis. WB436B can suppress tumor growth and metastasis in pancreatic cancer mouse models, extending the survival of tumor-bearing mice. |
| 靶点： |
STAT3 |
| 体内研究： |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
| 保存条件： |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.291 ml |
11.455 ml |
22.91 ml |
| 5 mM |
0.458 ml |
2.291 ml |
4.582 ml |
| 10 mM |
0.229 ml |
1.146 ml |
2.291 ml |
| 50 mM |
0.046 ml |
0.229 ml |
0.458 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京