| 产品描述： | SNX281 is a systemically active non-CDN STING agonist that binds to the STING protein. SNX281 promotes signal transduction of the cGAS-STING pathway, and increases cellular responses to tumor cells. SNX281 activates STING and leads to the production of type I IFNs and proinflammarory cytokines, ultimately stimulating the infilatration of immune cells into the tumor microenvironment. SNX281 enhances anti-tumor immunity, potentially overcoming resistance to checkpoint inhibitors in some cancer. SNX281 can be used in the research for anti-tumor immunity. |
| 体内研究： |
G-418 (500 μg/mL，12 days) 用于筛选耐药性 LNCaP 细胞。 |
| 保存条件： |
-80°C 6个月; -20°C 1个月,避光 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.565 ml |
12.824 ml |
25.648 ml |
| 5 mM |
0.513 ml |
2.565 ml |
5.13 ml |
| 10 mM |
0.256 ml |
1.282 ml |
2.565 ml |
| 50 mM |
0.051 ml |
0.256 ml |
0.513 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京