SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement.
体内研究:
SENP1-IN-3 improves the sensitivity of tumor cells to irradiation. SENP1-IN-3 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM.