| 产品描述： | Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers. |
| 靶点： |
Camptothecins |
| 体内研究： |
喜树碱衍生物是一类具有细胞毒性的小分子，可用于抗体药物偶联物的制备。喜树碱衍生物一般通过抑制拓扑异构酶 I 而具有抗肿瘤作用。 |
| 保存条件： |
-80°C 12个月; -20°C 6个月, 干燥 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.488 ml |
17.438 ml |
34.876 ml |
| 5 mM |
0.698 ml |
3.488 ml |
6.975 ml |
| 10 mM |
0.349 ml |
1.744 ml |
3.488 ml |
| 50 mM |
0.07 ml |
0.349 ml |
0.698 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京