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USP7-IN-9

    
10mM in DMSO

源叶(MedMol)
V57911 一键复制产品信息
2444374-01-8
C32H33ClF6N6O8
779.08
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
V57911-1ml
10mM in DMSO

¥4940.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoproteins MDM2 and DNMT1 and increases the protein levels of tumor suppressors p53 and p21.
体内研究: USP7-IN-9 (compound L55) (0-50 μM; 3 or 6 days) exhibits inhibitory activity against cancer cells.
USP7-IN-9 (1 μM; 0-72 hours) reduces the proportions of G2/M cells, and does not change the proportions of G0/G1 and S cells.
USP7-IN-9 (0.1-1 μM; 24 hours) reduces the protein levels of MDM2 and DNMT1 in a dose-dependent manner, and increases the protein levels of p53 and p21.
保存条件: -80°C 12个月; -20°C 6个月, 干燥
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.284 ml 6.418 ml 12.836 ml
5 mM 0.257 ml 1.284 ml 2.567 ml
10 mM 0.128 ml 0.642 ml 1.284 ml
50 mM 0.026 ml 0.128 ml 0.257 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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