| 产品描述： | (R)-Benpyrine is the isomer of Benpyrine , and can be used as an experimental control. Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. |
| 参考文献： |
1. Weiguang Sun, et al. Discovery of an Orally Active Small Molecule TNF-α Inhibitor. J Med Chem. 2020 Jul 15.
|
| 保存条件： |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.243 ml |
16.216 ml |
32.432 ml |
| 5 mM |
0.649 ml |
3.243 ml |
6.486 ml |
| 10 mM |
0.324 ml |
1.622 ml |
3.243 ml |
| 50 mM |
0.065 ml |
0.324 ml |
0.649 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京