| 产品描述: | O,O-Dimethyl-cannabigerol is a natural product from Cannabis sativa. O,O-Dimethyl-cannabigerol has an antibacterial effect on drug-resistant strains of Staphylococcus aureus (MIC ranging from 1 to 2 μg/mL). O,O-Dimethyl-cannabigerol is a nonpsychoactive constituent. |
| 体内研究: |
O,O-Dimethyl-cannabigerol (compound 1) inhibits KB cells growth with IC50s of 44.55 μM (MTT assay) and 69.4 μM (SRB assay). O,O-Dimethyl-cannabigerol (0-100 μM; 48 hours) induces cell cytotoxic in NIH 3T3 fibroblasts, with CD50s of 60.46 μM (MTT assay) and 82.98 μM (SRB assay). O,O-Dimethyl-cannabigerol shows antitumor efficacy against melanoma cells of a mouse's skin with an IC50 of 31.3 μM. |
| 参考文献: |
1. Appendino G, et al. Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. J Nat Prod. 2008;71(8):1427-1430. |
| 保存条件: |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.903 ml |
14.513 ml |
29.025 ml |
| 5 mM |
0.581 ml |
2.903 ml |
5.805 ml |
| 10 mM |
0.29 ml |
1.451 ml |
2.903 ml |
| 50 mM |
0.058 ml |
0.29 ml |
0.581 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |