| 产品描述: | MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC50 value of 1.7 μM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection. |
| 体内研究: |
MKA031 (compound 6y) (1-100 μl;3 h) 阻止 MNNG 诱导的细胞死亡。 MKA031 (compound 6y) (100 μl;3 h) 通过阻断 MIF 向 AIF 的募集来保护基因组 DNA。 |
| 保存条件: |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.479 ml |
12.393 ml |
24.786 ml |
| 5 mM |
0.496 ml |
2.479 ml |
4.957 ml |
| 10 mM |
0.248 ml |
1.239 ml |
2.479 ml |
| 50 mM |
0.05 ml |
0.248 ml |
0.496 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |