| 产品描述： | TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM. |
| 体内研究： |
TDP1 Inhibitor-2 (compound 5) shows potent anti-TDP1 activity, low cytotoxicity and synergism with topotecan, an established Top1 anticancer agent. |
| 保存条件： |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.149 ml |
10.746 ml |
21.492 ml |
| 5 mM |
0.43 ml |
2.149 ml |
4.298 ml |
| 10 mM |
0.215 ml |
1.075 ml |
2.149 ml |
| 50 mM |
0.043 ml |
0.215 ml |
0.43 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京