| 产品描述： | IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1). |
| 靶点： |
IL-2;IL-1 |
| 体内研究： |
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed. |
| 参考文献： |
1. Schnyder J, et al. Inhibition of interleukin-1 release by IX 207-887. Agents Actions. 1990 Jun;30(3-4):350-62.
|
| 保存条件： |
-80°C 6个月;-20°C 1个月 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.517 ml |
17.585 ml |
35.17 ml |
| 5 mM |
0.703 ml |
3.517 ml |
7.034 ml |
| 10 mM |
0.352 ml |
1.759 ml |
3.517 ml |
| 50 mM |
0.07 ml |
0.352 ml |
0.703 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京