产品介绍

(S)-(-)-α,α-二苯基-2-吡咯烷甲醇是一种双功能有机催化剂。应用(S)-(-)-α,α-二苯基-2-吡咯烷乙醇 (DPPM) 可用于以下过程：DPPM 与儿茶酚硼烷反应生成螺硼酸酯，它可以成为苯乙酮硼烷还原合成对映体纯醇的高效催化剂。二苯甲酮与硼烷-二乙基苯胺原位反应生成的催化剂，能有效地催化 2′ 的对映选择性还原-氟苯乙酮。用 DPPM 功能化的介孔 SBA-15 硅胶可以催化二乙基锌与苯甲醛加成形成 (S)-1-苯基-丙醇。用于制备对应的噁唑硼烷，噁唑硼烷可用于酮的硼烷介导不对称还原反应。;(S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol is a bifunctional organocatalyst.Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.(S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol (DPPM) may be used in the following processes:DPPM reacts with catecholborane to form a spiroborate ester, which can be an efficient catalyst for the synthesis of enantiopure alcohols by borane reduction of acetophenone.The catalyst generated in situ by reacting DPPM with borane-diethylaniline, can efficiently catalyze the enantioselective reduction of 2′-fluoroacetophenone.Mesoporous SBA-15 silica functionalized with DPPM can catalyze the addition of diethylzinc to benzaldehyde to form (S)-1-phenyl-propanol.