| 体内研究: |
In isolated rat hearts, concentrations of Adrenochrome from 1 to 1000 ng/mL increases coronary pressure in a dose- and time-dependent manner. Furthermore, the degree of constriction by Adrenochrome is dependent on the CaCl2 concentration in the perfusion medium. |
| 参考文献: |
1. M Karmazyn,, et al. Adrenochrome-induced coronary artery constriction in the rat heart. J Pharmacol Exp Ther. 1981 Oct;219(1):225-30. 2. S Takeo,et al. Effects of adrenochrome on calcium accumulating and adenosine triphosphatase activities of the rat heart microsomes. J Pharmacol Exp Ther. 1980 Sep;214(3):688-93. 3. Koji Ueda, et al. Catecholamine oxidation-mediated transcriptional inhibition in Mn neurotoxicity. J Toxicol Sci. 2020;45(10):619-624. |
| 保存条件: |
-20℃ |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
5.581 ml |
27.906 ml |
55.813 ml |
| 5 mM |
1.116 ml |
5.581 ml |
11.163 ml |
| 10 mM |
0.558 ml |
2.791 ml |
5.581 ml |
| 50 mM |
0.112 ml |
0.558 ml |
1.116 ml |
|
| 注意: |
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