| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
Y41302-1mg促销 |
97% | ￥950.00 ￥750.00 |
10 | - | - | - | - |
|
Y41302-5mg促销 |
97% | ￥2720.00 ￥2170.00 |
9 | - | - | - | - |
|
Y41302-10mg促销 |
97% | ￥4010.00 ￥3200.00 |
6 | - | - | - | - |
|
Y41302-25mg促销 |
97% | ￥6260.00 ￥5000.00 |
3 | - | - | - | - |
|
Y41302-50mg促销 |
97% | ￥8440.00 ￥6750.00 |
2 | - | - | - | - |
|
Y41302-100mg促销 |
97% | ￥10000.00 ￥7990.00 |
2 | - | - | - | - |
|
Y41302-250mg促销 |
97% | ￥18000.00 ￥14390.00 |
1 | - | - | - | - |
|
| 靶点： | IC50: 14 nM (serotonin), 20 nM (norepinephrine), 78 nM (dopamine). | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 体内研究： | Acute treatment of DOV-216,303 (20 mg/kg, i.p.) significantly increases dopamine, norepinephrine and serotonin levels in both OBX and Sham animals. Chronic treatment with DOV 216,303 (20 mg/kg, i.p., for 17 days) increases extracellular concentrations of dopamine, norepinephrine and serotonin in the medial prefrontal cortex of both OBX and Sham animals and significantly increases extracellular baseline serotonin concentrations. |
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| 参考文献： | 1. Shao L, et al. Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1438-41. 2. Prins J, et al. The putative antidepressant DOV 216,303, a triple reuptake inhibitor, increases monoamine release in the prefrontal cortex of olfactory bulbectomized rats. Eur J Pharmacol. 2010 May 10;633(1-3):55-61. |
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| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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营业执照(三证合一)
北京