货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
Y65350-1mg	98%	￥7080.00 Y65350-1mg ￥7080.00 2-4周	0 货期：2-4周	-	-	-	-
Y65350-5mg	98%	￥14000.00 Y65350-5mg ￥14000.00 2-4周	0 货期：2-4周	-	-	-	-

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靶点：

Angiotensin AT1 receptor

体内研究：

To verify this hypothesis, B2-/- or wild-type mice (B2+/+) are administered a nonpeptide antagonist of Ang II type 1 (AT1) receptors (A81988) from conception through 180 days of age. Untreated B2+/+ and B2-/- served as controls. Blood pressure (BP) and heart rate are monitored with the use of tail-cuff plethysmography at regular intervals. Ventricular weights, diameters, wall thickness, chamber volume, and myocardial fibrosis are measured at 40 and 180 days. No differences are observed in BP, heart rate, and cardiac weight and dimensions between treated and untreated B2+/+. The BP of AT1 antagonist-treated B2-/- is reduced until 70 days; then, it increases to the levels found in untreated B2-/-. AT1 receptor blockade results in a reduction in left ventricular mass, chamber volume, and wall thickness and abrogated myocardial fibrosis in B2-/-. A81988 (A-81988) decreases the BP of Bk2r-/- either in normosodic conditions or after sodium deprivation, whereas in Bk2r+/+ it produces a modest decrease under hyposodic conditions only.

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.413 ml	12.064 ml	24.128 ml
5 mM	0.483 ml	2.413 ml	4.826 ml
10 mM	0.241 ml	1.206 ml	2.413 ml
50 mM	0.048 ml	0.241 ml	0.483 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

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