品牌：源叶(MedMol)

产品编号：Y68366 一键复制产品信息

CAS号：130464-84-5

分子式：C₂₃H₃₀N₃NaO₄S₂

分子量：499.62

别名：(2S,3R)-N-羟基-N'-[(2S)-1-甲基氨基-1-氧代-3-苯基丙-2-基]-3-异丁基-2-(噻吩-2-基硫甲基)丁二酰胺单钠盐;巴马司他单钠盐;(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)bu

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
Y68366-1mg	98%	￥540.00 Y68366-1mg ￥540.00 2-3天	0 货期：2-3天	-	-	-	-
Y68366-5mg买3赠1	98.05%	￥1050.00 Y68366-5mg ￥1050.00 现货（买3赠1）	1 1	-	-	-	-

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靶点：

IC50: 3 nM (MMP-1), 4 nM (MMP-2), 4 nM (MMP-9), 6 nM (MMP-7), 20 nM (MMP-3)

体内研究：

Intraperitoneal administration of Batimastat (BB-94) effectively blocks growth of human ovarian carcinoma xenografts and murine melanoma metastasis and delays the growth of primary tumors in an orthotopic model of human breast cancer without cytotoxicity and without affecting mRNA levels. Batimastat (BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Treatment with Batimastat (60 mg/kg i.p. every other day, for a total of eight injections) concomitantly with Cisplatin (4 mg/kg i.v., every 7 days for a total of three injections) completely prevents growth and spread of both xenografts, and all animals are alive and healthy on day 200. Kaplan-Meier analysis of survival (at 48 h) shows that animals treated with Batimastat (BB-94) have increased survival (95.2%) in comparison with controls (75%), and differences are almost statistically significant (p=0.064). Matrix density is analyzed in saline- or Batimastat (40 mg/kg)-pretreated animals 4 h after E2 administration, the time point at which collagen density is observed to be at its lowest after hormone treatment.

保存条件：

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.002 ml	10.008 ml	20.015 ml
5 mM	0.4 ml	2.002 ml	4.003 ml
10 mM	0.2 ml	1.001 ml	2.002 ml
50 mM	0.04 ml	0.2 ml	0.4 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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浓度

体积

分子摩尔量

计算重置

(2S,3R)-N-羟基-N'-[(2S)-1-甲基氨基-1-氧代-3-苯基丙-2-基]-3-异丁基-2-(噻吩-2-基硫甲基)丁二酰胺单钠盐

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)