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EC 3.4.23.5

活力定义： If assayed as a proteinase, a unit of catheptic activity is defined as the amount of enzyme which causes an increase of 0.001 Unit extinction/minute of digestion of the substrate at 37°C.

If assayed as an amidase, a unit of amidase activity is defined as that amount of enzyme which produces a 1% hydrolysis of substrate Amide/minute at 37°C. This same unit definition is used if the esterase or hydrolase procedure are employed to assay cathepsin activity.

If assayed as a transferase, a unit of catheptic activity is defined as the amount of enzyme required to catalyze the formation of 1 mole of hydroxamic acid/minute at 37°C.

备注：The pH optimum used in defining a unit of enzyme activity will be determined by the type of cathepsin being assayed.