| 产品描述： | PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor. |
| 靶点： |
PD-1/PD-L1 |
| 细胞实验： |
PDL-1 cpd 10 demonstrated to strongly bind with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter.PDL-1 cpd 10 significantly increased interferon γ release and apoptotic induction of cancer cells, with low cytotoxicity in healthy cells. |
| 参考文献： |
Interfering with the Tumor–Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors |
| 溶解性： |
Soluble in DMSO |
| 保存条件： |
RT |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.649 ml |
13.247 ml |
26.494 ml |
| 5 mM |
0.53 ml |
2.649 ml |
5.299 ml |
| 10 mM |
0.265 ml |
1.325 ml |
2.649 ml |
| 50 mM |
0.053 ml |
0.265 ml |
0.53 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京