首页
订购/客服:400-666-5481

紫杉醇

    
分析标准品,含量99.0%,可溯源

Paclitaxel

源叶
A10255 一键复制产品信息
33069-62-4
C47H51NO14
853.92
MFCD00869953
泰素,紫素,特素 taxal;TAXOL;EMPAC;Onxal
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
A10255-30mg
分析标准品,含量99.0%,可溯源

¥350.00

>10 4 2 - -
A10255-50mg
分析标准品,含量99.0%,可溯源

¥500.00

>10 3 2 - -
产品介绍 参考文献(24篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Paclitaxel 是一种天然抗肿瘤药,可稳定微管蛋白 (tubulin) 的聚合。Paclitaxel 可导致有丝分裂停滞和诱导细胞凋亡 (apoptosis),最终导致细胞死亡。Paclitaxel 还可诱导细胞自噬 (autophagy)。

SMILES: O=C1[C@H](OC(C)=O)C(C2(C)C)=C(C)[C@@H](OC([C@H](O)[C@@H](NC(C3=CC=CC=C3)=O)C4=CC=CC=C4)=O)C[C@@]2(O)[C@@H](OC(C5=CC=CC=C5)=O)[C@@]6([H])[C@@]1(C)[C@@H](O)C[C@@]7([H])OC[C@]76OC(C)=O
熔点: 213-216°C
沸点: 957.115 °C at 760 mmHg
比旋光度: -49.0°-55.0°(甲醇)
外观: 白色结晶体粉末
溶解性: DMSO  :  100  mg/mL  (117.11  mM;  Need  ultrasonic)

H2O  :  <  0.1  mg/mL  (insoluble)
储存条件: 2-8℃
密度: 1.39
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(24篇)

19. [IF=4.7] Hongyan Lin, et al. "EGFR/tubulin dual-targeting podophyllotoxin triazole ester derivatives: Design, synthesis, and anti-NSCLC activity evaluation"JOURNAL OF MOLECULAR STRUCTURE, 2026 Jul;1364:145923 18. [IF=4.6] Wenlong Nie, et al. "Enhanced paclitaxel oral delivery by astragalus polysaccharide-based nanoplatform for triple-negative breast cancer treatment"Nanomedicine-Nanotechnology Biology and Medicine, 2026 Apr;:102947 17. [IF=4.8] Zheng Ye et al."Polyphyllin H Reverses Paclitaxel Resistance in Breast Cancer by Binding Membrane Cholesterol to Inhibit Both ABCB1 and ABCC3."Pharmaceuticals.2025 Nov;18(11):1699 16. [IF=8.3] Min Jiang et al."Membrane Cholesterol-Dependent Dual VEGFR2/FGFR1 Inhibition by Ginsenoside Rg3 to Overcome Gefitinib Resistance in NSCLC."PHYTOMEDICINE.2025 Oct;:157421 15. [IF=12.6] Lan Jinshuai et al."Astragalus polysaccharide-based nano-platforms loading PTX to boost chemo-immunotherapy for triple-negative breast cancer with intrinsic GLUT-targeting ability and immunoregulatory activity."JOURNAL OF NANOBIOTECHNOLOGY.2025 Dec;23(1): 14. [IF=8.2] Yue Wang et al."Nanometabolomics Elucidated Paclitaxel/Mo4/3B2–x Bifunctional Nanomedicine-Based Lung Cancer Therapy through Regulated Amino Acid Metabolism."ACS Applied Materials & Interfaces.2025;17(40):55833–55847 13. [IF=8.2] Zhenhui Luo et al."Cavidine alleviates paclitaxel-induced peripheral neuropathy by promoting mitochondrial autophagy through inhibiting PKM2-mediated histone lactylation."FREE RADICAL BIOLOGY AND MEDICINE.2025 Sep;: 12. [IF=8.3] Shufang Li et al."Daphnetin as a novel polyphosphate kinase inhibitor to combat Salmonella infection."PHYTOMEDICINE.2025 Nov;148:157278 11. [IF=4.4] Shuo Wang et al."Targeted PHA Microsphere-Loaded Triple-Drug System with Sustained Drug Release for Synergistic Chemotherapy and Gene Therapy."Nanomaterials.2024 Jan;14(20):1657 10. [IF=6.8] Mengzhen Gu et al."Target Ligand Separation and Identification of Isoforsythiaside as a Histone Lysine-Specific Demethylase 1 Covalent Inhibitor Against Breast Cancer Metastasis."JOURNAL OF MEDICINAL CHEMISTRY.2024;67(21):19874–19888 9. [IF=3.3] Shuqin Li et al."Double-crosslinked hydrogels and hydrogel beads formed by garlic protein hydrolysates for bioactive encapsulation and gastrointestinal delivery."JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE.2024 Nov;: 8. [IF=3.8] Xiu-mei Luan et al."Improvement of polarity-based solvent system for countercurrent chromatography in the guidance of solvent selectivity: n-hexane/ethyl acetate/ alcohol solvents/water as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Nov;1736:465389 7. [IF=5.5] Hongji Pu et al."Antiproliferative agent attenuates post-thrombotic vein wall remodeling in murine and human subjects."JOURNAL OF THROMBOSIS AND HAEMOSTASIS.2024 Sep;: 6. [IF=4.4] Qu Minmin et al."Assessing genotoxic effects of chemotherapy agents by a robust in vitro assay based on mass spectrometric quantification of γ-H2AX in HepG2 cells."Frontiers in Pharmacology.2024 Jun;15: 5. [IF=5.1] Danli Cao et al."Cannabidiol Inhibits Epithelial Ovarian Cancer: Role of Gut Microbiome."JOURNAL OF NATURAL PRODUCTS".2024;XXXX(XXX):XXX-XXX 4. [IF=4.6] Han Tao et al."Development of an invasion score based on metastasis-related pathway activity profiles for identifying invasive molecular subtypes of lung adenocarcinoma."Scientific Reports.2024 Jan;14(1):1-16 3. [IF=4.6] Liying Xiao et al."Silk Nanofiber Carriers for both Hydrophilic and Hydrophobic Drugs to Achieve Improved Combination Chemotherapy."MACROMOLECULAR BIOSCIENCE.2024 Jan;:2300523 2. [IF=4.5] Zirui Zhao et al."Transcriptomics and Physiological Analyses Reveal Changes in Paclitaxel Production and Physiological Properties in Taxus cuspidata Suspension Cells in Response to Elicitors."Plants-Basel.2023 Jan;12(22):3817 1. [IF=5] Haizhu Xing et al."Thymoquinone Alleviates Paclitaxel-Induced Peripheral Neuropathy through Regulation of the TLR4-MyD88 Inflammatory Pathway."ACS Chemical Neuroscience.2023;XXXX(XXX):XXX-XXX

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×