140. [IF=2.7] Yuan Xu et al."Hua Yu Xiao Zheng decoction induces ectopic endometrial stromal cell senescence via inhibiting the PI3K/AKT signaling."TISSUE & CELL.2025 Jan;:102763 139. [IF=4.2] Jiaoyue Zhu et al."Investigating the Formation and Molecular Solubilization Mechanism of Emodin Solid Dispersions by Molecular Dynamics Simulation."MOLECULES.2025 Jan;30(4):822 138. [IF=7.1] Jiahui Gong et al."Smart Dual-Responsive Ionic Liquid as Transformable and Recyclable Media for Extracting and Separating Phytochemicals from Wild Rumex acetosa L.."ACS Sustainable Chemistry & Engineering.2024;XXXX(XXX):XXX-XXX 137. [IF=6.7] Kaixin Liu et al."Polydatin mitigates thrombosis by inhibiting PHD2-induced proline hydroxylation on collagen, reducing platelet adhesion."PHYTOMEDICINE.2025 Mar;138:156392 136. [IF=4.7] Yijie Li et al."Anthraquinones of Cassiae Semen alleviate lipid accumulation in obesity by regulating brown adipose tissue and liver function."Chinese Herbal Medicines.2025 Feb;: 135. [IF=6.1] Jia Guo et al."Discovery of anthraquinones as potent Notum inhibitors for treating osteoporosis by integrating biochemical, phytochemical, computational, and experimental assays."Journal of Pharmaceutical Analysis.2025 Mar;:101256 134. [IF=4.8] Ke-han Chen et al."Evaluating the efficacy and safety of emodin, luteolin, and paeonol combination from Dahuang Mudan decoction in ameliorating ulcerative colitis."JOURNAL OF ETHNOPHARMACOLOGY.2025 Apr;346:119692 133. [IF=4.8] Chunying Li et al."A green and sustainable synthesis of polydopamine molecularly imprinted resin for selective recognition emodin in Rumex acetosa L.: experiments and simulation."Food Bioscience.2025 Apr;:106674 132. [IF=1.5] Qian Xiaojing et al."Qualitative, Quantitative Analysis and Pharmacokinetic Study of Potentially Active Components of Huangxueyishen Decoction Based on UPLC-MS/MS."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2025 Apr;63(4): 131. [IF=4.3] Chenghao Zhang et al."Emodin nanocrystals enhanced mucus penetration and ameliorated bleomycin-induced pulmonary fibrosis by pulmonary delivery."JOURNAL OF DRUG TARGETING. 130. [IF=3.8] Haitao Wang et al."Combination of Metabolomics, Lipidomics, and Molecular Biology for the Investigation of the Metabolic Disturbance of Short-Term Administration of Emodin."JOURNAL OF PROTEOME RESEARCH.2024;23(10):4327–4342 129. [IF=6.6] Wenyu Zhang et al."Biomimetic Iron-Based Nanoparticles Remodel Immunosuppressive Tumor Microenvironment for Metabolic Immunotherapy."International Journal of Nanomedicine. 128. [IF=4.9] Xiaoran Zhao et al."Constructing a hydrogel based on self-assembly properties of glycyrrhizic acid: A drug delivery system with digestive tract responsive."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2024 Sep;697:134497 127. [IF=8.5] Guangfu Feng et al."Natural Flavonoid-Derived Enzyme Mimics DHKNase Balance the Two-Edged Reactive Oxygen Species Function for Wound Healing and Inflammatory Bowel Disease Therapy.."Research.2024 Sep;7:0464-0464 126. [IF=1.3] Ze-Ye Tan et al."Correlation analysis between potential hepatotoxicity and ingredient content of polygoni multiflori caulis."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 125. [IF=3.9] Xiong Weijian et al."Emodin inhibits M1 macrophage activation that related to acute and chronic kidney injury through EGFR/MAPK pathway."FUNCTIONAL & INTEGRATIVE GENOMICS.2024 Aug;24(4):1-13 124. [IF=5.3] Chuanxi Tian et al."Exploring the therapeutic efficacy: Unveiling the active compounds of Huashi Baidu granules against COVID-19."Arabian Journal of Chemistry.2024 Sep;17:105910 123. [IF=10.6] Hou Yu et al."Integrated oral microgel system ameliorates renal fibrosis by hitchhiking co-delivery and targeted gut flora modulation."JOURNAL OF NANOBIOTECHNOLOGY.2024 Dec;22(1):1-21 122. [IF=7.9] Huiyi Song et al."Emodin nanocapsules inhibit acute pancreatitis by regulating lipid metabolic reprogramming in macrophage polarization."PHYTOMEDICINE".2024 Jul;130:155763 121. [IF=3.9] Yibao Wei et al."Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study."EXPERIMENTAL GERONTOLOGY".2024 Jun;190:112413 120. [IF=2] Lin Zhou et al."Therapeutic Potential of Danyankang Capsule in High-Fat Diet-Induced Cholelithiasis and Its Impact on Liver FXR Signaling and Gut Microbiota."BIOLOGICAL & PHARMACEUTICAL BULLETIN".2024 Mar;47(3):680-691 119. [IF=5.6] Tong Qingheng et al."Integrated chemical characterization, metabolite profiling, and pharmacokinetics analysis of Zhijun Tangshen Decoction by UPLC-Q/TOF-MS."Frontiers in Pharmacology".2024 Mar;15: 118. [IF=7.5] Yong-Guang Liu et al."Anti-inflammatory effect and pharmacokinetics of dehydroandrographolide, an active component of Andrographis paniculata, on Poly(I:C)-induced acute lung injury."BIOMEDICINE & PHARMACOTHERAPY".2024 May;174:116456 117. [IF=3.1] Liuxuan Yang et al."Biomimetic delivery of emodin via macrophage membrane-coated UiO-66-NH2 nanoparticles for acute pancreatitis treatment."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS".2024 Apr;702:149649 116. [IF=4.3] Fan Xinyu et al."A comprehensive investigation on the chemical changes of traditional Chinese medicine with classic processing technology: Polygonum multiflorum under nine cycles of steaming and sunning as a case study."ANALYTICAL AND BIOANALYTICAL CHEMIS 115. [IF=4.9] Zhao Xia et al."Comparative transcriptome analysis and identification of candidate R2R3-MYB genes involved in anthraquinone biosynthesis in Rheum palmatum L.."Chinese Medicine".2024 Dec;19(1):1-18 114. [IF=4.1] Xiaoyao Liu et al."The Water Extract of Rhubarb Prevents Ischemic Stroke by Regulating Gut Bacteria and Metabolic Pathways."Metabolites".2024 Apr;14(4):216 113. [IF=2.7] Ding-Wen Cheng et al."Emodin inhibits HDAC6 mediated NLRP3 signaling and relieves chronic inflammatory pain in mice."Experimental and Therapeutic Medicine.2024 Jan;27(1):1-7 112. [IF=8.2] Yanli Wang et al."β-1,3-d-glucan particles-based “nest” protected co-loaded Rhein and Emodin regulates microbiota and intestinal immunity for ulcerative colitis treatment."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Dec;:128818 111. [IF=8.8] Feng Xiong et al."Geographical verification of Pleuropterus multiflorus thunb. by functional compounds, stable isotope ratios, and multielement combined with machine learning methods."FOOD CHEMISTRY.2024 May;440:138209 110. [IF=4.8] Yan Lan et al."Polygonum Cuspidatum Alcohol Extract Exerts Analgesic Effects via the MAPK/ERK Signaling Pathway."Drug Design Development and Therapy. 109. [IF=4.5] Guangtao Pan et al."Dachengqi decoction ameliorates sepsis-induced liver injury by inhibiting the TGF-β1/Smad3 pathways."Journal of Traditional and Complementary Medicine.10.1016/j.jtcme.2023.09.001 108. [IF=2.9] Qi Ying et al."Sanhuang Xiexin Decoction Ameliorates TNBC By Modulating JAK2-STAT3 and Lipid Metabolism."Chinese Journal of Integrative Medicine.2023 Nov;:1-10 107. [IF=3.4] Si Li et al."Active ingredients of Erhuang Quzhi Granules for treating non-alcoholic fatty liver disease based on the NF-κB/NLRP3 pathway."FITOTERAPIA.2023 Dec;171:105704 106. [IF=5.4] Bo Zhang et al."Integration of single-nucleus RNA sequencing and network disturbance to elucidate crosstalk between multicomponent drugs and trigeminal ganglia cells in migraine."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;319:117286 105. [IF=3.2] Zhongjie Hua et al."Emodin protects against intestinal dysfunction and enhances survival in rat model of septic peritonitis through anti-inflammatory actions."Immunity Inflammation and Disease.2023 Aug;11(8):e942 104. [IF=10.2] Lei Fenting et al."Oral hydrogel nanoemulsion co-delivery system treats inflammatory bowel disease via anti-inflammatory and promoting intestinal mucosa repair."JOURNAL OF NANOBIOTECHNOLOGY.2023 Dec;21(1):1-19 103. [IF=3.1] Cuicui Liu et al."Identification and quantitative analysis of the chemical constituents of Gandouling tablets using ultra-high-performance liquid chromatography with quadrupole time-of-flight mass spectrometry."JOURNAL OF SEPARATION SCIENCE.2023 Jun;:2300 102. [IF=5.4] Jie Tang et al."Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro."JOURNAL OF ETHNOPHARMACOLOGY.2023 Nov;316:116780 101. [IF=7.3] Li Chen et al."Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via Nur77-mediated epigenetic regulation of GLS1."BRITISH JOURNAL OF PHARMACOLOGY.2023 Jun;: 100. [IF=8.2] Jia Wan et al."Chitosan-based double network hydrogel loading herbal small molecule for accelerating wound healing."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Aug;246:125610 99. [IF=3.776] Lele Zhang et al."Integration of UHPLC/Q-OrbitrapMS-based metabolomics and activities evaluation to rapidly explore the anti-inflammatory components from lasianthus.."Heliyon.2023 May;9(6):e16117-e16117 98. [IF=4.601] Yuexuan Li et al."Facile and selective separation of anthraquinones by alizarin-modified iron oxide magnetic nanoparticles."JOURNAL OF CHROMATOGRAPHY A.2023 Aug;1702:464088 97. [IF=3.242] Xu Chenyu et al."The active compound in Rheum officinale Baill, aloe-emodin promotes tomato seedling growth."PLANT GROWTH REGULATION.2023 Mar;:1-14 96. [IF=3.614] Liqing Wang et al."Discovery of the potential neuraminidase inhibitors from Polygonum cuspidatum by ultrafiltration combined with mass spectrometry guided by molecular docking."JOURNAL OF SEPARATION SCIENCE.2023 Mar;:2200937 95. [IF=6.656] Yanchao Xing et al."Cytochrome P450-mediated herb-drug interaction (HDI) of Polygonum multiflorum Thunb. based on pharmacokinetic studies and in vitro inhibition assays."PHYTOMEDICINE.2023 Feb;:154710 94. [IF=3.37] Dingwen Cheng et al."Emodin Alleviates Arthritis Pain through Reducing Spinal Inflammation and Oxidative Stress."Molecular Pain. 93. [IF=6.656] Chong Chen et al."Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling."PHYTOMEDICINE.2022 Nov;:154546 92. [IF=3.571] Lin Zhou et al."Comprehensive investigation on the metabolism of emodin both in vivo and in vitro."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Jan;223:115122 91. [IF=3.614] Li Ji et al."Characterization of the chemical constituents and metabolic profile of Polygonum cuspidatum Sieb. et Zucc. in rat plasma, urine, and feces by ultra-high performance liquid chromatography coupled with Quadrupole-Exactive Orbitrap mass spectrom 90. [IF=3.645] Xi Zhou et al."Preparation of magnetic metal-organic framework MIL-101(Fe) and its application in the extraction of anthraquinones in rhubarb."JOURNAL OF SEPARATION SCIENCE 89. [IF=4.36] Zhenhui Guo et al."Study on the mechanism of Cortex Lycii on lung cancer based on network pharmacology combined with experimental validation."J Ethnopharmacol. 2022 Apr;:115280 88. [IF=5.811] Kong Wei-Song et al."Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury."Front Pharmacol. 2022 Apr;0:928 87. [IF=4.432] Yanqing Wang et al.Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission.Eur J Pharmacol. 2021 Nov;:174603 86. [IF=6.165] Yaofen Li et al.Study on the effects of deep eutectic solvents as a reaction media on the micromorphology of hydrogen-substituted graphyne and its adsorption and electrochemical properties.J Mol Liq. 2021 Nov;:118177 85. [IF=0.986] Ji-le Lan et al."Q-marker Prediction Analysis of Rhubarb in Fengyin Decoction Based on Fingerprint and Network Pharmacology:."Nat Prod Commun. 2021;16(8): 84. [IF=1.618] Tao Yi et al."Simultaneous Quantitation of Five Bioactive Ingredients in Raw and Processed Fallopia multiflora by Employing UHPLC-Q-TOF-MS."J Chromatogr Sci. 2019 Aug;57(7):618-624 83. [IF=1.902] Chenxi Wang et al."Multiple component-pharmacokinetic studies on 10 bioactive constituents of Peiyuan Tongnao capsule using parallel reaction monitoring mode."Biomed Chromatogr. 2021 Oct;35(10):e5153 82. [IF=2.161] Jinjing Li et al."Enhanced hydrophilicity and antifouling performance of PES-C/emodin ultrafiltration membrane:."High Perform Polym. 0;(): 81. [IF=2.401] Yongqian Huang et al."The intervention mechanism of emodin on TLR3 pathway in the process of central nervous system injury caused by herpes virus infection."Neurol Res. 2021;43(4):307-313 80. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 79. [IF=3.205] Jie Tang et al."Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."J Chromatogr B. 2021 Aug;1179:122827 78. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328 77. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002 76. [IF=3.935] Li Xie et al."Development of an UHPLC-MS/MS method for comparative pharmacokinetics of nine anthraquinones in rats and application to dosage conversion between different Semen Cassiae forms."J Pharmaceut Biomed. 2019 Sep;174:696 75. [IF=3.935] Yanchao Xing et al."An effective strategy for distinguishing the processing degree of Polygonum multiflorum based on the analysis of substance and taste by LC-MS, ICP-OES and electronic tongue."J Pharmaceut Biomed. 2021 Oct;205:114328 74. [IF=3.943] Yuanyuan Liu et al."Emodin ameliorates ovalbumin-induced airway remodeling in mice by suppressing airway smooth muscle cells proliferation."Int Immunopharmacol. 2020 Nov;88:106855 73. [IF=4.092] Shen Pan et al."Emodin Attenuates Acetaminophen-Induced Hepatotoxicity via the cGAS-STING Pathway."Inflammation. 2021 Aug;:1-14 72. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 71. [IF=4.36] Li Lin et al."Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism."J Ethnopharmacol. 2020 Apr;252:112577 70. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625 69. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra 68. [IF=5.645] Li-Xia Dai et al."Ultrasound-assisted extraction of five anthraquinones from Rheum palmatum water extract residues and the antimicrobial activities."Ind Crop Prod. 2021 Apr;162:113288 67. [IF=5.81] Zhihui Yin et al."Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis."Front Pharmacol. 2021; 12: 746711 66. [IF=5.81] Zhang N et al."Emodin Inhibits the Proliferation of MCF-7 Human Breast Cancer Cells Through Activation of Aryl Hydrocarbon Receptor (AhR).."Front Pharmacol. 2020 Jan;11:622046-622046 65. [IF=6.165] Neng Qiu et al."Inclusion complex of emodin with hydroxypropyl-β-cyclodextrin: Preparation, physicochemical and biological properties."J Mol Liq. 2019 Sep;289:111151 64. [IF=9.811] Manjie Gao et al."High-Crystallinity Covalent Organic Framework Synthesized in Deep Eutectic Solvent: Potentially Effective Adsorbents Alternative to Macroporous Resin for Flavonoids."Chem Mater. 2021;33(20):8036–8051 63. [IF=1.773] Li-Hua ZHOU et al."Label-free quantitative proteomics reveals fibrinopeptide B and heparin cofactor II as potential serum biomarkers in respiratory syncytial virus-infected mice treated with Qingfei oral liquid formula."Chin J Nat Medicines. 2018 Apr;16:2 62. [IF=1.843] Ma Libin et al."Emodin ameliorates renal fibrosis in rats via TGF-β1/Smad signaling pathway and function study of Smurf 2."Int Urol Nephrol. 2018 Feb;50(2):373-382 61. [IF=3.361] Lailai Li et al."Development of a dual screening strategy to identify pro-angiogenic compounds from natural products: application on Tongmai Yangxin Pills."Rsc Adv. 2016 Dec;6(116):115308-115316 60. [IF=3.366] Wu Xingqiang et al."A Novel Selective Accelerated Solvent Extraction for Effective Separation and Rapid Simultaneous Determination of Six Anthraquinones in Tartary Buckwheat and Its Products by UPLC–DAD."Food Anal Method. 2015 May;8(5):1124-1132 59. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56 58. [IF=4.366] Longfei Lin et al."Inhibition of Mitochondrial Complex Function—The Hepatotoxicity Mechanism of Emodin Based on Quantitative Proteomic Analyses."Cells-Basel. 2019 Mar;8(3):263 57. [IF=4.411] Yanling Zeng et al."Rapid Characterization of Components in Bolbostemma paniculatum by UPLC/LTQ-Orbitrap MSn Analysis and Multivariate Statistical Analysis for Herb Discrimination."Molecules. 2018 May;23(5):1155 56. [IF=4.743] Hua Jun-yi et al."Emodin prevents intima thickness via Wnt4/Dvl-1/β-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery rats."Exp Mol Med. 2015 Jun;47(6):e170-e170 55. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 54. [IF=5.645] Fangyuan Gao et al."Cyclodextrin-based ultrasonic-assisted microwave extraction and HPLC-PDA-ESI-ITMSn separation and identification of hydrophilic and hydrophobic components of Polygonum cuspidatum: A green, rapid and effective process."Ind Crop Prod. 20 53. [IF=9.229] Qing-Shan Liu et al."Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture."Acs Appl Mater Inter. 2017;9(7):5725–5732 52. Zhou, Li-Hua, et al. "Label-free quantitative proteomics reveals fibrinopeptide B and heparin cofactor II as potential serum biomarkers in respiratory syncytial virus-infected mice treated with Qingfei oral liquid formula." Chin J Nat Med 16 (2018): 241-25 51. Zhou, Li-Hua, et al. "Label-free quantitative proteomics reveals fibrinopeptide B and heparin cofactor II as potential serum biomarkers in respiratory syncytial virus-infected mice treated with Qingfei oral liquid formula." Chin J Nat Med 16 (2018): 241-25 50. Huang, Xiya, Weixi Cai, and Baojun Xu. "Kinetic changes of nutrients and antioxidant capacities of germinated soybean (Glycine max L.) and mung bean (Vigna radiata L.) with germination time." Food chemistry 143 (2014): 268-276.https://doi.org/10.1016/j.foo 49. LIU, Qing-Shan, et al. Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture. ACS applied materials & interfaces, 2017, 9.7: 5725-5732.https://doi.org/10.1021/acsami.6b13477 48. Zhang, Ning, et al. "Emodin inhibits the proliferation of human breast cancer MCF-7 cells through activation of aryl hydrocarbon receptor." Frontiers in Pharmacology 11 (2020): 2372.https://doi.org/10.3389/fphar.2020.622046 47. Qiu, Neng, et al. "Inclusion complex of emodin with hydroxypropyl-β-cyclodextrin: Preparation, physicochemical and biological properties." Journal of Molecular Liquids 289 (2019): 111151.https://doi.org/10.1016/j.molliq.2019.111151 46. Lin, Longfei, et al. "Inhibition of Mitochondrial Complex Function—The Hepatotoxicity Mechanism of Emodin Based on Quantitative Proteomic Analyses." Cells 8.3 (2019): 263.https://doi.org/10.3390/cells8030263 45. Huang, Yongqian, et al. "The intervention mechanism of emodin on TLR3 pathway in the process of central nervous system injury caused by herpes virus infection." Neurological Research 43.4 (2021): 307-313.https://doi.org/10.1080/01616412.2020.1853989 44. Wang, Qi, et al. "Identification and characterization of the structure–activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum." Scientific reports 7.1 (2017): 1-9. 43. Gao, Fangyuan, et al. "Cyclodextrin-based ultrasonic-assisted microwave extraction and HPLC-PDA-ESI-ITMSn separation and identification of hydrophilic and hydrophobic components of Polygonum cuspidatum: A green, rapid and effective process." Industrial Cro 42. 张明明. 大黄道地产区核心种质构建及优良种质筛选研究[D].北京中医药大学,2020. 41. 汪颖舒,朱广灏,王冰,李杰荣,骆前飞,何修滢,赵佳逸,修彦凤.古法黑豆蒸晒与药典黑豆汁连续蒸对何首乌中12个成分含量的影响[J].中草药,2020,51(19):4972-4982. 40. 王盼,储全根,轩云,蔡正银.抵当陷胸汤HPLC-MS指纹图谱研究[J].时珍国医国药,2020,31(12):2937-2940. 39. 李承浩,王萌,任晓亮.磺化杯6芳烃对4类中药单体成分增溶作用及其机制研究[J].中国现代中药,2020,22(12):2032-2038. 38. 佘瑶瑶,刘自华,张颖,刘义梅,陈运中.湖北虎杖主要化学成分的含量分析及其与色差的相关性研究[J].食品安全质量检测学报,2021,12(03):960-967. 37. 周桂,谢瑞芳,于天源,周昕.首乌藤指纹图谱的建立及3种成分的测定[J].中医药导报,2020,26(13):27-32. 36. 宁一博,程龙,黄芷棋,贺润铖,孙建宁,董世芬.基于脂肪棕色化探究大黄素对老龄小鼠脂质代谢的影响[J].中南药学,2021,19(03):478-483. 35. 陆杰,王婷婷,梁琨,安叡,王新宏,陈颖.UPLC-LTQ-Orbitrap-MS法分析大承气汤化学成分[J].中成药,2020,42(12):3275-3280. 34. 陈静.pH响应的铜-大黄素脂质体的制备及其体外释放研究[J].江苏科技信息,2020,37(31):52-54. 33. 周军, 彭媚, 陈薇,等. 药用虎杖剩余物的化学组成与热解特性[J]. 环境工程学报, 2018, 12(12):229-237. 32. 刘全德,唐仕荣,宋慧,王营,邢洪伟.芦荟蒽醌类化合物的超声提取及其抗氧化性研究[J].食品与机械,2011,27(05):68-71. 31. 郭允, 陈永超, 李晓花,等. 牛黄解毒片中6种指标成分的含量测定[J]. 沈阳药科大学学报, 2016(6):454-458. 30. 杨强 蒲晓辉 李晓花. 一清胶囊中7种指标成分的测定[J]. 华西药学杂志 2017(3). 29. 李晓花 郭允 李佳 袁琦 蒲晓辉 王高峰.RP-HPLC法同时测定三黄片中7种指标成分的含量[J].沈阳药科大学学报 2016 33(08):637-642. 28. 魏艳婷 张静宜 张华潭 等. HPLC法同时测定三黄滴丸中5种蒽醌类成分的含量[J]. 中国药房 2015. 27. 程素盼 张敏敏 梁琰 等. HPLC-DAD-ESI-TOF/MS法分析安神补脑液中化学成分[J]. 中成药 2019 041(004):743-748. 26. 李红英 向极钎 龙澜 等. HPLC法测定大黄药材中5种游离蒽醌的含量[J]. 安徽农业科学 2013(12):5278-5279. 25. 徐艳, 张心怡, 狄留庆,等. 基于热熔挤出技术的虎杖提取物速释固体分散体制备研究[J]. 中草药, 2017(23):4865-4871. 24. 周杨静,唐俊峰,高峰,卫培峰.基于“九蒸九晒”炮制法的何首乌主要化学成分含量变化及对大鼠肝脏的影响实验研究[J].中南药学,2020,18(04):543-548. 23. 杨国静 张珞琪 陈随清 等. 不同商品规格决明子的质量分析[J]. 中国现代中药 2018 v.20(08):963-967. 22. 支旭然 刘洪涛 吴茵 等. UPLC-MS/MS法同时测定肾康注射液中7个有效成分[J]. 药物分析杂志 2017 037(001):37-42. 21. 支旭然, 白万军, 王祁民,等. 肾康注射液的配伍稳定性考察[J]. 中国药师, 2016, 19(011):2155-2157. 20. 林艳, 刘月新, 李春,等. 生/制何首乌HPLC指纹图谱结合模式识别与含量测定的质量控制研究[J]. 中国中医药信息杂志, 2018, 25(12):67-71. 19. 王亚洲, 吴洪文. 烫伤合剂质量标准研究[J]. 中国医院药学杂志, 2012, 32(021):1767-1769. 18. 蔡芳, 任繁栋, 任达兵,等. 整合定性策略用于大黄素代谢物的高通量靶向鉴定[J]. 分析化学, 2019, 047(008):1212-1218. 17. 李宵 吴茵 支旭然 等. UPLC-MS/MS法同时测定苦黄注射液中7种成分的含量[J]. 中国药房 2017 028(015):2108-2112. 16. 支旭然 董占军 吴茵 等. HPLC同时测定肾康注射液中的4种成分[J]. 华西药学杂志 2017(03):297-299. 15. 张蕾, 郭晏华, 黄婷,等. 虎杖生品及不同炮制品中虎杖苷、白藜芦醇和大黄素含量[J]. 辽宁中医药大学学报, 2013, 015(011):56-59. 14. 顾玲, 闫璟, 柯苗,等. 芦丁在聚大黄素/纳米氧化锌修饰碳糊电极上的电化学行为研究[J]. 化学研究与应用, 2017(10). 13. 李成职, 刘洋, 刘小红,等. 消痔方醇提工艺和颗粒制剂含量测定方法[J]. 青岛大学学报(工程技术版), 2018, 033(001):130-134. 12. 张丹参, 梅艳飞, 宋晓敏,等. 大黄结肠靶向微丸的制备及处方优化[J]. 中草药, 2016, 47(008):1321-1326. 11. 张丹参, 梅艳飞, 宋晓敏,等. 大黄结肠靶向微丸在大鼠胃肠道内的分布及释放方法学研究[J]. 神经药理学报, 2015, 5(005):20-27. 10. 赵滋苗, 蔡宛如, 陆军,等. 大黄素对脓毒症大鼠血糖和胰岛素抵抗的影响[J]. 中国现代应用药学, 2016, 33(009):1115-1118. 9. 韦美金,黄娟,白俊其,蔡锡潮,丘小惠.大黄素对大鼠血清肝功能、肝脏转运蛋白及代谢酶UGT1A1表达的影响[J].时珍国医国药,2018,29(07):1551-1555. 8. 豆颖, 闫哲, 潘翔珍,等. 大黄素对口腔鳞癌细胞Tca8113抑制作用[J]. 医药论坛杂志, 2015(01):72-74. 7. 郝宗艳, 李欣, 李玲. 大黄素对功能性消化不良大鼠相关指标影响的实验研究[J]. 新中医, 2017, 049(005):1-3. 6. 王云龙, 郭海, 魏睦新. 大黄素对CCl4诱导小鼠肝纤维化的作用机制[J]. 中国现代中药, 2018, 20(04):402-408. 5. 李灵玲, 蒲吉, LI,等. 大黄素促进结肠癌细胞自噬性凋亡的作用及其机制[J]. 华西药学杂志, 2017, 06(v.32):46-49 4. 江坤, 李璐, 李菁,等. 基于抗炎药效的中药榕须质量评价研究[J]. 中国药学杂志, 2016, 051(012):1033-1038. 3. 孟雨婷, 李华, 陈志颖,等. 基于成分检测的大黄-蜇虫药对最佳配伍比例的研究[J]. 辽宁化工, 2020, v.49;No.459(01):32-36. 2. 葛朝亮 程钢 余剑萍 许杜娟.“九蒸九晒”传统炮制对何首乌主要化学成分的影响[J].现代中药研究与实践 2017 31(03):43-47. 1. 陈帅 王慧竹 薛健飞 等. HPLC-DAD法同时测定四季三黄丸中9种成分[J]. 中成药 2016(8期):1727-1731.