品牌：源叶

产品编号：B24469 一键复制产品信息

CAS号：95058-81-4

分子式：C₉H₁₁F₂N₃O₄

分子量：263.2

MDL：MFCD00869720

别名：4-氨基-1-[3,3-二氟-4-羟基-5-(羟甲基)氧杂环戊-2-基]嘧啶-2-酮;双氟脱氧胞苷;4-氨基-1-(3,3-二氟-4-羟基-5-羟甲基四氢呋喃-2-基)-1H-嘧啶-2-酮;吉西他宾;吉西他滨碱;GemCltabine

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
B24469-20mg	分析标准品,HPLC≥99%	￥200.00 B24469-20mg ￥200.00 现货	222 4 >10	2	2	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

B24469-20mg

分析标准品,HPLC≥99%

￥200.00

>10

产品介绍

Gemcitabine (LY 188011) 是一种嘧啶核苷类似物抗代谢药 (nucleoside antimetabolite/analog) 和抗肿瘤剂。Gemcitabine 抑制 DNA 合成 (DNA synthesis) 和修复，导致细胞自噬 (autophagy) 和凋亡 (apoptosis)

SMILES：	[C@H]2(N1C(N=C(N)C=C1)=O)C([C@H](O)[C@H](O2)CO)(F)F
熔点：	168.64 °C
沸点：	482.7°C at 760 mmHg
比旋光度：	365 +425.36°; D +71.51°
外观：	粉末
溶解性：	DMSO : 250 mg/mL (949.85 mM; Need ultrasonic) Ethanol : 12.5 mg/mL (47.49 mM; Need ultrasonic) H2O : 6.25 mg/mL (23.75 mM; ultrasonic and warming and heat to 60°C)
储存条件：	2-8℃
密度：	1.84
注意：	部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(10篇)

10. [IF=4.9] Jiexin Zhang, et al. "Compound 17 Inhibits Lung Cancer Progression via Inducing Cellular Apoptosis and Blocking TNF Signaling Pathway Activation"INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2026 Feb;27(4):1693 9. [IF=5.2] Ying Xu, et al. "Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation"Journal of Integrative Medicine-JIM, 2026 May;: 8. [IF=3.9] Chi Qinglong et al."Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches."Scientific Reports.2025 Jun;15(1):1-21 7. [IF=4.4] Shuo Wang et al."Targeted PHA Microsphere-Loaded Triple-Drug System with Sustained Drug Release for Synergistic Chemotherapy and Gene Therapy."Nanomaterials.2024 Jan;14(20):1657 6. [IF=9.4] Wenkai Zhang et al."Manganese nanosheets loaded with selenium and gemcitabine activate the tumor microenvironment to enhance anti-tumor immunity."JOURNAL OF COLLOID AND INTERFACE SCIENCE.2025 Mar;682:556

5. [IF=3] Silli Epiphane K. et al."Design optimization of Fucoidan-coating Cationic Liposomes for enhance Gemcitabine delivery."INVESTIGATIONAL NEW DRUGS.2024 Aug;:1-13 4. [IF=5.062] Mengfei Li et al."FU-coating pH-sensitive liposomes for improving the release of gemcitabine by endosome escape in pancreatic cancer cells."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2023 Feb;80:104135 3. [IF=8.039] Haohao Wang et al."Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle."JOURNAL OF MEDICINAL CHEMISTRY.2022;XXXX(XXX):XXX-XXX 2. [IF=2.311] Shanshan Jiang et al."Combination treatment of gemcitabine and sorafenib exerts a synergistic inhibitory effect on non‑small cell lung cancer in vitro and in vivo via the epithelial‑to‑mesenchymal transition process."Oncol Lett. 2020 Jul;20(1):346-356 1. [IF=6.304] Xiong Qiao et al."Cuprous oxide nanoparticles trigger reactive oxygen species-induced apoptosis through activation of erk-dependent autophagy in bladder cancer."Cell Death Dis. 2020 May;11(5):1-13

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