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盐酸多奈哌齐

    
分析标准品,HPLC≥98%

Donepezil Hydrochloride

源叶
B25489 一键复制产品信息
110119-84-1
C24H30ClNO3
415.95
2-[(1-苄基-4-哌啶基)甲基]-5,6-二甲氧基-2,3-二氢-1-茚酮盐酸盐;An oxidized polyethylene wax
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
B25489-100mg促销
分析标准品,HPLC≥98%

¥240.00 ¥200.00

8 2 1 - 2
产品介绍 参考文献(28篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

SMILES: COc1cc2CC(CC3CCN(CC3)Cc4ccccc4)C(=O)c2cc1OC
沸点: 527.9°C at 760 mmHg
外观: 白色结晶
溶解性: DMSO  :  6.2  mg/mL  (14.91  mM)
储存条件: 2-8℃
密度: 1.141
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(28篇)

23. [IF=6.7] Gai Gao et al."Shenghui Decoction inhibits neuronal cell apoptosis to improve Alzheimer's disease through the PDE4B/cAMP/CREB signaling pathway."PHYTOMEDICINE.2025 Jan;:156366 22. [IF=7.9] Zhou Fulin et al."Cornuside alleviates cognitive impairments induced by Aβ1−42 through attenuating NLRP3-mediated neurotoxicity by promoting mitophagy."Alzheimers Research & Therapy.2025 Dec;17(1):1-22 21. [IF=3.8] Ren Ruichen et al."Nebulized seabuckthorn seed oil inhalation attenuates Alzheimer’s disease progression in APP/PS1 mice."Scientific Reports.2025 Feb;15(1):1-14 20. [IF=4.8] Jin-Qiu Li et al."Isoliensinine ameliorates cognitive dysfunction in AlCl3/D-gal-induced Alzheimer’s disease-like mice by inhibiting the calcium signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2025 Mar;344:119567 19. [IF=7.1] Shuhan Wang et al."Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway."FREE RADICAL BIOLOGY AND MEDICINE.2025 May;232:72 18. [IF=3.4] Zhijuan Tang et al."Neuroprotective effect of Licochalcone A against aluminum chloride-induced neurotoxicity by reducing Aβ accumulation, oxidative stress and inflammatory reaction."NEUROTOXICOLOGY.2025 May;108:295 17. [IF=12.2] Xueying Xu et al."β-ionone inhibits the grazing of Daphnia sinensis by reducing the activity of acetylcholinesterase."JOURNAL OF HAZARDOUS MATERIALS.2024 Nov;479:135690 16. [IF=4.5] Zhang Lingyu et al."GSK3β Substrate-competitive Inhibitors Regulate the gut Homeostasis and Barrier Function to Inhibit Neuroinflammation in Scopolamine-induced Alzheimer’s Disease Model Mice."INFLAMMATION.2024 Aug;:1-22 15. [IF=13.6] Wenkai Chen et al."β-cyclocitral, a novel AChE inhibitor, contributes to the defense of Microcystis aeruginosa against Daphnia grazing."JOURNAL OF HAZARDOUS MATERIALS.2023 Dec;:133248 14. [IF=5.6] Haojie Ni et al."Levistilide A ameliorates neuroinflammation via inhibiting JAK2/STAT3 signaling for neuroprotection and cognitive improvement in scopolamine-induced Alzheimer’s disease mouse model."INTERNATIONAL IMMUNOPHARMACOLOGY.2023 Nov;124:110783 13. [IF=6.212] Nanxi Zhang et al."Based on 1H NMR and LC-MS metabolomics reveals biomarkers with neuroprotective effects in multi-parts ginseng powder."Arabian Journal of Chemistry.2023 Jul;16:104840 12. [IF=6.656] Yinhuang Gao et al."Modified Erchen decoction ameliorates cognitive dysfunction in vascular dementia rats via inhibiting JAK2/STAT3 and JNK/BAX signaling pathways."PHYTOMEDICINE.2023 Mar;:154797 11. [IF=5.895] Hantao Zhang et al."Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;XXXX(XXX):XXX-XXX 10. [IF=5.34] Mengnan Zeng et al."Corallodiscus flabellata B. L. Burtt extract and isonuomioside A ameliorate Aβ25−35-induced brain injury by inhibiting apoptosis, oxidative stress, and autophagy via the NMDAR2B/CamK Ⅱ/PKG pathway."PHYTOMEDICINE. 2022 Jul;101:154114 9. [IF=3.252] Mengnan Zeng et al."Adenosine ameliorated Aβ25−35-induced brain injury through the inhibition of apoptosis and oxidative stress via an ERα pathway."BRAIN RESEARCH. 2022 Aug;1788:147944 8. [IF=2.557] Hongyan Wang et al."Donepezil down-regulates propionylation, 2-hydroxyisobutyrylation, butyrylation, succinylation, and crotonylation in the brain of bilateral common carotid artery occlusion-induced vascular dementia rats."Clin Exp Pharmacol P. 2020 Oct; 7. [IF=3.038] Bing Cao et al."Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in A β 25−35 -Induced Mice by mTOR Signaling."Neurochem Res. 2021 Apr;46(4):921-934 6. [IF=5.076] Wan Ting et al."FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling."Oxid Med Cell Longev. 2019;2 5. [IF=5.34] Dongli Li et al."Systems pharmacology approach uncovers the therapeutic mechanism of medicarpin against scopolamine-induced memory loss."Phytomedicine. 2021 Oct;91:153662 4. 李洁,毛宇,蒋可欣,马磊,王蕊.丹参酮ⅡA通过改善线粒体功能和氧化应激减轻大鼠认知障碍[J].华东理工大学学报(自然科学版),2021,47(01):48-57. 3. 周伟, 庾国桢, 刘亚敏,等. 黄芩苷通过IκBα/NF-κB通路调节Aβ25-35诱导的HT22细胞凋亡[J]. 中成药, 2019, 041(011):2765-2769. 2. 于修芳, 雷霞, 曹玲,等. 补阳还五汤对阿尔茨海默病小鼠海马凋亡因子及学习记忆能力的影响[J]. 中国实验方剂学杂志, 2018, 24(03):109-113. 1. 薛姣 顾业伟 韩玉谦. DHA型磷脂酰丝氨酸对东莨菪碱痴呆模型小鼠学习记忆力的影响[J]. 中国海洋药物 2020 039(001):26-30.

质检证书(COA)

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摩尔浓度计算器

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