| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80668-2mg买3赠1 |
99.10% | ￥300.00 |
5 | - | - | - | - |
|
S80668-5mg买3赠1 |
99.10% | ￥400.00 |
5 | - | - | - | - |
|
S80668-10mg买3赠1 |
99.10% | ￥640.00 |
4 | - | - | - | - |
|
S80668-25mg促销 |
99.10% | ￥1240.00 ￥992.00 |
5 | - | - | - | - |
|
S80668-50mg促销 |
≥99% | ￥1990.00 ￥1590.00 |
货期：2-3天 | - | - | - | - |
|
S80668-100mg促销 |
≥99% | ￥3920.00 ￥3130.00 |
货期：2-3天 | - | - | - | - |
|
S80668-200mg促销 |
≥99% | ￥5360.00 ￥4280.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | Optovin is a reversible photoactivated TRPA1 ligand that enables light-mediated neuronal excitation. Optovin activates TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues | ||||||||||||||||||||
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| 靶点： | TRP Channel;TRP/TRPVChannel | ||||||||||||||||||||
| 体外研究： | Optovin (1-10 μM) increases Zebrafish embryos motor activity greater than 40 standard deviations above the control mean at the photic stimuli, with an EC50 of 2 μM. Optovin (100 μM; 120 s) strongly activates 33% (35/105) of dorsal root ganglia (DRG) neurons. Optovin (10 μM; 1 min) activates HEK293T cells transfected with hTrpA1 | ||||||||||||||||||||
| 体内研究： | Optovin (1-10 μM) causes light-dependent motor excitation in vivo. Optovin (15 mM (20 μL); on the ear) elicits nociceptive behaviors in adult mice. Optovin (10 μM; 96 h) do not affect the appearance, touch response, heart rate, fin movements, morphology or percentage survival of larvae and adult zebrafish | ||||||||||||||||||||
| 参考文献： | 1. Kokel D, et al. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr;9(4):257-63. | ||||||||||||||||||||
| 溶解性： | soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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北京