| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S85528-5mg |
99.7% | ￥637.00 | 6 | - | - | - |
|
S85528-10mg |
99.7% | ￥950.00 | 6 | - | - | - |
|
S85528-25mg |
99.7% | ￥1960.00 | 4 | - | - | - |
|
S85528-50mg |
≥99% | ￥3300.00 | 货期：2-3天 | - | - | - |
|
HI-TOPK-032 is a potent and specific TOPK inhibitor.
| 产品描述： | HI-TOPK-032 is a potent and specific TOPK inhibitor. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | TOPK | ||||||||||||||||||||
| 体内研究： | Treatment of mice with 1 or 10 mg/kg of HI-TOPK-032 significantly inhibits HCT-116 tumor growth by more than 60% relative to the vehicle-treated group. Mice are well tolerated with HI-TOPK-032 treatment. The expression of p53 is strongly induced, and phosphorylation of ERK and RSK, a direct downstream protein of ERK, is markedly inhibited in the HI-TOPK-032-treated group | ||||||||||||||||||||
| 参考文献： | 1. Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15;72(12):3060-8. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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