| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T71273-5mg促销 |
99.90% | ￥100.00 ￥90.00 |
6 | - | - | - | - |
|
T71273-10mg |
99.90% | ￥160.00 |
6 | - | - | - | - |
|
T71273-25mg |
99.90% | ￥350.00 |
6 | - | - | - | - |
|
T71273-100mg |
≥98% | ￥1000.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | McN-A 343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis. | ||||||||||||||||||||
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| 靶点： | AChR | ||||||||||||||||||||
| 体内研究： | After the induction of 6% acetic acid colitis, treatment with McN-A 343 at a concentration of 1.5 mg/kg showed a significant reduction in intestinal damage as well as a decrease in wet weight, MPO activity, pro-inflammatory cytokine concentration, markers of oxidative stress and expression of inflammatory mediator | ||||||||||||||||||||
| 参考文献： | 1. Koss MC, et al. Analysis of miosis produced by McN-A-343 in anesthetized cats. J Ocul Pharmacol Ther. 1995;11(3):389-399. 2. Magalhães DA, Batista JA, Sousa SG, et al. McN-A-343, a muscarinic agonist, reduces inflammation and oxidative stress in an experimental model of ulcerative colitis. Life Sci. 2021;272:119194. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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