货号	规格	价格	上海	北京	珠海	重庆	武汉
T72905-5mg促销	99.50%	￥270.00 ￥216.00 T72905-5mg ￥216.00 现货	4 0 4	-	-	-	-
T72905-10mg促销	99.50%	￥500.00 ￥400.00 T72905-10mg ￥400.00 现货	6 6	-	-	-	-
T72905-25mg促销	99.50%	￥990.00 ￥792.00 T72905-25mg ￥792.00 现货	5 5	-	-	-	-
T72905-100mg促销	≥98%	￥2630.00 ￥2100.00 T72905-100mg ￥2100.00 2-3天	0 货期：2-3天	-	-	-	-

大包装询价收藏产品

加入购物车

产品描述：

A 1070722 is a potent and selective GSK-3 inhibitor, shows high affinity GSK-3α(Ki = 0.6 nM) and GSK-3β(Ki = 0.6 nM). It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain

靶点：

GSK-3α:0.6 nM (ki), GSK-3β:0.6 nM (ki);GSK-3

体内研究：

PET imaging experiments in anesthetized vervet/African green monkey exhibited that A 1070722 penetrated the blood-brain barrier (BBB) and accumulated in brain regions, with highest radioactivity binding in frontal cortex followed by parietal cortex and anterior cingulate, and with the lowest bindings found in caudate, putamen, and thalamus, similarly to the known distribution of GSK-3 in human brain

参考文献：

1. Prabhakaran J, et al. Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci. 2017 Aug 16;8(8):1697-1703.

溶解性：

Soluble in DMSO

保存条件：

2-8°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.76 ml	13.8 ml	27.601 ml
5 mM	0.552 ml	2.76 ml	5.52 ml
10 mM	0.276 ml	1.38 ml	2.76 ml
50 mM	0.055 ml	0.276 ml	0.552 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置