(Rac)-lunresertib (compound 181) is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. (Rac)-lunresertib (compound 181) has anticancer effects.
靶点:
PKMYT1
参考文献:
1. Daniel Durocher, et al. Methods of using myt1 inhibitors. WO2021195782A1.