产品介绍

来自Sigma的酶已用于分析硫酸皮肤素十二糖中艾杜糖醛酸的频率。它也被用于消化黑素瘤细胞中的硫酸皮肤素（DS）。这种消化导致癌细胞的增殖和侵袭性降低，从而显示了DS在转移中的作用。来自肝素黄杆菌的软骨素酶B已用于评估硫酸皮肤素的结构表征和抗凝血酶活性的研究中。肝素黄杆菌的软骨素酶B也已用于通过液相色谱-质谱法研究软骨素裂解酶的作用方式的研究中。;Chondroitinase B from Flavobacterium heparinum has been used in a study to assess the structural characterization and antithrombin activity of dermatan sulfate. Chondroitinase B from Flavobacterium heparinum has also been used in a study to investigate the chondroitin lyase action pattern via liquid chromatography–mass spectrometry.The enzyme from Sigma has been used for the analysis of the frequency of iduronic acid in dermatan sulfate dodecasaccharide. It has also been used to digest dermatan sufate (DS) in melanoma cells. This digestion resulted in decreased proliferation and invasiveness of tumor cells, thereby suggesting a role for DS in metastasis.