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人参皂苷Rd

    
分析标准品,含量90.4%,可溯源

Ginsenoside Rd

源叶
A10276 一键复制产品信息
52705-93-8
C48H82O18
947.15
MFCD00210508
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
A10276-20mg
分析标准品,含量90.4%,可溯源

¥480.00

>10 - - - -
产品介绍 参考文献(42篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Ginsenoside Rd 抑制 TNFα 诱导的 NF-κB 转录活性,IC50 为 12.05±0.82 μM。Ginsenoside Rd 抑制 COX-2 和 iNOS mRNA 的表达。Ginsenoside Rd 还抑制 Ca2+ 内流。Ginsenoside Rd 抑制CYP2D6,CYP1A2,CYP3A4 和 CYP2C9,IC50 分别为 58.0±4.5 μM,78.4±5.3 μM,81.7±2.6 μM 和 85.1±9.1 μM。

SMILES: C[C@](CC/C=C(C)/C)([C@]1([H])[C@]([C@H](O)C[C@@]2([H])[C@@]3(C)CC[C@]4([H])[C@]2(C)CC[C@H](O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)([H])[C@@]3(C)CC1)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O
熔点: 204-206°C
沸点: 1020.4°C at 760 mmHg
比旋光度: +19.38(c=1.03,甲醇)
外观: 白色粉末(乙醇-乙酸乙酯 1:1)
溶解性: DMSO  :  100  mg/mL  (105.58  mM;  Need  ultrasonic)
敏感性: 易吸潮
储存条件: 2-8℃
密度: 1.37
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(42篇)

37. [IF=3.3] Yang-Bin Lai, et al. "Allelopathic metabolite accumulation and microbial dysbiosis underlying continuous cropping disorder in the Panax ginseng rhizosphere"PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 2026 Mar;142:103128 36. [IF=3.7] Siqi Liu, et al. "Metabolomics and Microbiomics Reveal the Cultivation-Dependent Divergence in Ginsenoside Biosynthesis and Rhizosphere Ecology of Panax ginseng"Metabolites, 2026 Feb;16(2):138 35. [IF=5.9] Shanshan Li, et al. "Integrating colorimetry, chemical fingerprint, and immunological activity: A multidimensional strategy for ginseng quality control"Food Bioscience, 2026 Apr;78:108468 34. [IF=6.2] Min Gao, et al. "Immunoprotective potential of steamed Panax notoginseng saponins: chemical characterization and mechanistic insights via the TLRs/NF-κB pathway"Journal of Agriculture and Food Research, 2026 Mar;26:102754 33. [IF=8.5] Hanting Liu, et al. "A Cold-Adapted GH1 β-Glucosidase from Paenibacillus cellulosilyticus with high methanol tolerance for efficient biotransformation of ginsenoside Rb1 to minor ginsenoside F2"INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2026 Mar; 32. [IF=4.8] Zhufeng Cong, et al. "Investigation of the improvement effect of Dajianzhong decoction on rats with post-operative ileus based on serum metabolomics and spectrum-effect relationship"Frontiers in Pharmacology, 2026 Apr;17:1793033 31. [IF=5.9] Hao Lu, et al. "Metabolomics and Microbial Genomics Reveal the Beneficial Effects of Total Saponins from Red American Ginseng on Pre-diabetes in Mice"Food Bioscience, 2026 Apr;:108928 30. [IF=7.5] Yifan Cheng, et al. "Mechanisms of yield and quality enhancement in Panax Vietnamensis: A comparison of three artificial cultivation models"Journal of Ginseng Research, 2026 May;:101056 29. [IF=1.3] Leng Xingwang et al."Application of HPLC Combined with UPLC–Orbitrap-MS in Chemical Characterization, Quantitative Detection, and Species Authentication of Four Panax-Derived Products."CHROMATOGRAPHIA.2025 Dec;:1-17 28. [IF=8.3] Teng Liu et al."American ginseng -derived extracellular-like nanoparticles (AGELNs) mitigate doxorubicin-induced cardiotoxicity by inhibiting GPX4-mediated ferroptosis."PHYTOMEDICINE.2026 Jan;:157861 27. [IF=8.3] Yin Shi et al."Panax Notoginseng Saponins Ameliorate Spinal Cord Injury by Inhibiting JAK2/STAT3-Mediated Macrophage Polarization: Enhanced Delivery by Ultrasound-targeted Microbubble Destruction."PHYTOMEDICINE.2026 Jan;:157856 26. [IF=2.5] Qiaoxiang Wu et al."A new UDP-glycosyltransferase for rare ginsenoside biosynthesis from Gynostemma pentaphyllum (Thunb.)."CARBOHYDRATE RESEARCH.2025 Dec;558:109703 25. [IF=7.3] Xueni Yan et al."Green Biomanufacturing of High-Value Ginsenoside F2 Using β-Glucosidase Smbgl3 in a Tailored Deep Eutectic Solvent-Containing Buffer System."ACS Sustainable Chemistry & Engineering.2025;13(43):18689–18702 24. [IF=1.3] Ya-Ran Teng et al."Comparative pharmacokinetic studies on ginsenosides in the common and ultrafine granular powder of Panax ginseng by using UHPLC-MS/MS."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 23. [IF=2.6] Jieting Zhang et al."Quantification and discovery of quality control chemical markers for Shouhui Tongbian capsules by UPLC-MS/MS."Analytical Methods.2025 Aug;: 22. [IF=2.8] Yiying Tan et al."Screening of compounds in ginseng that activate CYP19A1 enzyme promoters for the treatment of postmenopausal osteoporosis using molecular docking and affinity ultrafiltration technology."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIE 21. [IF=4.8] Dongling Cai et al."Total ginsenosides enhance γ-globin expression and fetal hemoglobin production in β-thalassemia models."Frontiers in Pharmacology.2025 Aug;16: 20. [IF=2.6] Jieting Zhang et al."Quantification and discovery of quality control chemical markers for Shouhui Tongbian capsules by UPLC-MS/MS."Analytical Methods.2025 Aug;: 19. [IF=2.8] Yiying Tan et al."Screening of compounds in ginseng that activate CYP19A1 enzyme promoters for the treatment of postmenopausal osteoporosis using molecular docking and affinity ultrafiltration technology."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES 18. [IF=4.8] Dongling Cai et al."Total ginsenosides enhance γ-globin expression and fetal hemoglobin production in β-thalassemia models."Frontiers in Pharmacology.2025 Aug;16: 17. [IF=2.4] Peng Yidan et al."Chemical composition and transcriptomic analysis revealed the dynamic changes of saponins during the growth of Panax japonicus var. major."AoB Plants.2025 Jun;: 16. [IF=5.7] Liu Wenjing et al."The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease."Chinese Medicine.2025 Dec;20(1):1-21 15. [IF=8.5] Chengcheng Li et al."Cellulase hyperproduction Trichoderma reesei mutant strain BB8 for the bioextraction and bioconversion of ginsenoside from Panax notoginseng."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2025 Jun;:144984 14. [IF=9.8] Meng-Qi Liu et al."Identification of natural food-derived emulsifiers using QSAR and machine learning: Application in dairy emulsions."FOOD CHEMISTRY.2025 Jun;:145260 13. [IF=3.8] Qin Wei et al."Target Identification of Ginsenosides Against Cognitive Impairment by Using Mass Spectrometry-Based Cellular Thermal Shift Assay (CETSA)."NEUROCHEMICAL RESEARCH.2025 Jun;50(3):1-17 12. [IF=6.2] Peng Yu et al."Ginsenosides 20R-Rg3 and Rg5 enriched black ginseng inhibits colorectal cancer tumor growth by activating the Akt/Bax/caspase-3 pathway and modulating gut microbiota in mice."Current Research in Food Science.2025 Jan;10:100978 11. [IF=2.8] Ruobing Bai et al."Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity."JOURNAL OF CHROMATOGRAPHY B-ANALYTIC 10. [IF=7.7] Yiming Li et al."Protopanaxadiol (PPD)-type ginsenosides inhibit the key element of α-glucosidase - The glycosyl group."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2025 May;306:141843 9. [IF=6.8] Feiyan Chen et al."Identification of AIF1 as a protein target of notoginsenosides in brain tissue of mice with intracerebral hemorrhage based on hapten immunoaffinity fishing technique."Journal of Ginseng Research.2025 Apr;: 8. [IF=2.9] Ning Xu et al."Water extract of ginseng alleviates parkinsonism in MPTP–induced Parkinson’s disease mice."PLoS One.2024 Sep;19(9):e0296424 7. [IF=3.4] Sethuraman Sathya et al."Comparison of chemical components and quality evaluation of Panax ginseng and its processed products from different habitats in Northeastern China."Biocatalysis and Agricultural Biotechnology.2024 Oct;61:103375 6. [IF=3.8] Chen Yue et al."Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats."Scientific Reports.2024 Sep;14(1):1-12 5. [IF=4.3] Wu Dehua et al."Temperature seasonality and soil phosphorus availability shape ginseng quality via regulating ginsenoside contents."BMC PLANT BIOLOGY.2024 Dec;24(1):1-12 4. [IF=8.5] Jiabao Feng et al."Analysis of sediment re-formation factors after ginseng beverage clarification based on XGBoost machine learning algorithm."FOOD CHEMISTRY.2024 Sep;:141304 3. [IF=3.5] Hong Yinan et al."Biotransformation of ginsenoside compound K using β-glucosidase in deep eutectic solvents."BIOPROCESS AND BIOSYSTEMS ENGINEERING.2024 Jun;:1-11 2. [IF=5.9] Jing Fang et al."Effects of soil microbial ecology on ginsenoside accumulation in Panax ginseng across different cultivation years."INDUSTRIAL CROPS AND PRODUCTS".2024 Sep;215:118637 1. [IF=4.7] Sheng Hu et al."Ginsenoside Rd enhances blood-brain barrier integrity after cerebral ischemia/reperfusion by alleviating endothelial cells ferroptosis via activation of NRG1/ErbB4-mediated PI3K/Akt/mTOR signaling pathway."NEUROPHARMACOLOGY".2024 Jun;251:1

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