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丹参酮IIA

    
分析标准品,含量98.0%,可溯源

Tanshinone IIA

源叶
A10031 一键复制产品信息
568-72-9
C19H18O3
294.34
MFCD00238692
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
A10031-20mg
分析标准品,含量98.0%,可溯源

¥160.00

>10 - 4 - -

产品介绍

SMILES: CC1=COC(C2=C(C3=O)C(CCCC(C)4C)=C4C=C2)=C1C3=O
熔点: 205-207°C
沸点: 480.7°C at 760 mmHg
外观: 桔红色针状结晶
溶解性: 动物实验建议溶解方案:0.5%CMCNA+粉末超声做悬浊液1-2mg/ml。丹参酮IIA溶液状态下不稳定,需要现配现用,不能储备液形式储存。
储存条件: 2-8℃
密度: 1.209
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(51篇)

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[IF=5.5] Wencong Tian et al."Tanshinone IIA Alleviates Pyroptosis through SIRT1/NLRP3 Pathway to Improve Diabetic Nephropathy."AMERICAN JOURNAL OF CHINESE MEDICINE.2026 Jan;54(01):285-301 41. [IF=5.6] Yuexin Li et al."Lumacaftor and fexofenadine prevent donepezil-induced LQTS via PHE656-mediated hERG chaperoning."BIOCHEMICAL PHARMACOLOGY.2026 Mar;245:117681 40. [IF=7.9] Ping Huang et al."Purification optimization of tanshinones and their neuroprotection assessment on SH-SY5Y cells injured by oxygen-glucose deprivation/reoxygenation."Results in Engineering.2025 Oct;:107884 39. [IF=8.3] Fangqing Ning et al."Total tanshinones extract alleviates chronic prostatitis/chronic pelvic pain syndrome by modifying intestinal flora and suppressing the LPS-TLR4 axis."PHYTOMEDICINE.2025 Oct;:157458 38. [IF=8.5] Chaoyue Zheng et al."A magnetic nanoparticles-based ligand fishing method coupled with parallel artificial membrane permeability assay for rapid discovery and analysis of GSNO reductase inhibitors with good membrane permeability from Salvia miltiorrhiza B 37. [IF=2.5] Lu-Lu Cheng et al."TSA-SAB Co-Loaded Liposome Self-Dissolving Microneedle Synergistic Delivery System: A Breakthrough Dual-Drug Loading Strategy for Multi-Target Therapy of Hypertrophic Scars."PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. 36. [IF=2.6] Xiaoqian Huo et al."Mechanism analysis of Salvia miltiorrhiza Bunge (Danshen) on circadian rhythm for treating myocardial injury by mathematic model."FITOTERAPIA.2025 Oct;186:106782 35. [IF=4.3] Yiman Zou et al."Supramolecular Self-assembly of Tanshinone IIA to Construct an Antitumor Drug Delivery Platform."ACS Omega.2025;XXXX(XXX):XXX-XXX 34. [IF=2.5] Lu-Lu Cheng et al."TSA-SAB Co-Loaded Liposome Self-Dissolving Microneedle Synergistic Delivery System: A Breakthrough Dual-Drug Loading Strategy for Multi-Target Therapy of Hypertrophic Scars."PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. 33. [IF=2.6] Xiaoqian Huo et al."Mechanism analysis of Salvia miltiorrhiza Bunge (Danshen) on circadian rhythm for treating myocardial injury by mathematic model."FITOTERAPIA.2025 Oct;186:106782 32. [IF=4.3] Yiman Zou et al."Supramolecular Self-assembly of Tanshinone IIA to Construct an Antitumor Drug Delivery Platform."ACS Omega.2025;XXXX(XXX):XXX-XXX 31. [IF=10.2] Chenjie Xia et al."An efficient brain delivery system co-loaded with multiple components of Salvia miltiorrhiza for synergistic treatment of ischemic stroke."Materials Today Bio.2025 Jul;:102102 30. [IF=3.4] Wang Qiaona et al."Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H2O2-induced injury in PC12 cells."BMC Complementary Medicine and Therapies.2025 Dec;25(1):1-13 29. [IF=4] Lijuan Wu et al."Integration of chromatographic fractionation, quantitative 1H-NMR and serially coupled achiral-chiral LC–MS/MS enables multi-components-targeted determination of Salvia miltiorrhiza in an authentic compound-independent manner."JOURNAL OF 28. [IF=4.9] Kewei Zuo et al."Transcriptome- and Metabolome-Based Regulation of Growth, Development, and Bioactive Compounds in Salvia miltiorrhiza (Lamiaceae) Seedlings by Different Phosphorus Levels."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(13):6253 27. [IF=4.4] Liu Qi et al."Tanshinone IIA delays liver aging by modulating oxidative stress."Frontiers in Pharmacology.2024 Oct;15: 26. [IF=5.7] Xue-Zhang et al."Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX 25. [IF=6.7] Mingzhu Qi et al."Qingxin Jieyu Granule alleviates myocardial infarction through inhibiting neutrophil extracellular traps via activating ANXA1/FPR2 axis."PHYTOMEDICINE.2024 Dec;135:156147 24. [IF=5.7] Lichao Qian et al."In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma."Frontiers in Immunology.2024 Oct;15: 23. [IF=8.3] Ruiyan Zhu et al."Abscisic acid enhances SmAPK1-mediated phosphorylation of SmbZIP4 to positively regulate tanshinone biosynthesis in Salvia miltiorrhiza."NEW PHYTOLOGIST.2024 Nov;: 22. [IF=8.1] Sheng Wang et al."Target-oriented rational design of composite bio-derived solvents for the green extraction of salvianolic acid B and tanshinones from Salvia miltiorrhiza root."SEPARATION AND PURIFICATION TECHNOLOGY.2025 Jun;359:130772 21. [IF=3.8] Xu Wang et al."A HPLC-assisted mathematical prediction method of ternary solvent systems to develop an intelligent online selection system for countercurrent chromatography solvent system."JOURNAL OF CHROMATOGRAPHY A.2024 Dec;:465585 20. [IF=4.8] Zhirong Zhou et al."Dan-Shen-Yin against ethanol-induced chronic gastric mucosal injury in rats by inhibiting apoptosis via IP3R-controlled calcium release."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;:119413 19. [IF=4.8] Ke Cai et al."Absorption and metabolic transformation mechanisms of the interaction between salvianolic acids and tanshinones in DKD rats."JOURNAL OF ETHNOPHARMACOLOGY.2025 May;348:119885 18. [IF=13.3] Zhicheng Xiao et al."A novel nitric oxide-driven nanomotor for synergistic treatment of ischaemic stroke: Enhanced deep brain penetration and therapeutic efficacy."CHEMICAL ENGINEERING JOURNAL.2024 Sep;496:154205 17. [IF=2.8] Fang Liang et al."Therapeutic effects of Tanshinone IIA and Tetramethylpyrazine nanoemulsions on cognitive impairment and neuronal damage in Alzheimer’s disease rat models."JOURNAL OF PHARMACY AND PHARMACOLOGY.2024 Jun;: 16. [IF=6.2] Ying Ren et al."Effect of CeO2, TiO2 and SiO2 nanoparticles on the growth and quality of model medicinal plant Salvia miltiorrhiza by acting on soil microenvironment."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jul;280:116552 15. [IF=0.6] Hui Dong et al."Research on the Improvement of Endothelial Cell Function and Trophoblast Apoptosis in Rats with Preeclampsia by Tanshinone IIA."Pharmacognosy Magazine.;(): 14. [IF=2.6] Yan-Zhu Quan et al."The intervention mechanism of Tanshinone IIA in alleviating neuronal injury induced by HMGB1 or TNF-α-mediated microglial activation."TOXICOLOGY IN VITRO.2024 Dec;101:105950 13. [IF=3.8] Xiu-mei Luan et al."Improvement of polarity-based solvent system for countercurrent chromatography in the guidance of solvent selectivity: n-hexane/ethyl acetate/ alcohol solvents/water as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Nov;1736:465389 12. [IF=4.9] Zhongda Cao et al."Baicalin Inhibits FIPV Infection In Vitro by Modulating the PI3K-AKT Pathway and Apoptosis Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(18):9930 11. [IF=2.6] Cheng Shao et al."Local Application of Tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing in ovariectomized mice."Journal of Orthopaedic Surgery and Research".2024 Dec;19(1):1-12 10. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal 9. [IF=7.9] Mingyu Wu et al."Tanshinone IIA positively regulates the Keap1-Nrf2 system to alleviate pulmonary fibrosis via the sestrin2-sqstm1 signaling axis-mediated autophagy."PHYTOMEDICINE".2024 Apr;:155620 8. [IF=10.2] Guo Hong et al."Homologous-magnetic dual-targeted metal-organic framework to improve the Anti-hepatocellular carcinoma efficacy of PD-1 inhibitor."JOURNAL OF NANOBIOTECHNOLOGY".2024 Dec;22(1):1-20 7. [IF=1.8] Meile Ma et al."Tanshinone IIA Regulates Synaptic Plasticity in Mg2+-Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway."Journal of Integrative Neuroscience".2024 Mar;23(3):61 6. [IF=9.8] Ying Ren et al."Response of antioxidant activity, active constituent and rhizosphere microorganisms of Salvia miltiorrhiza to combined application of microbial inoculant, microalgae and biochar under Cu stress."SCIENCE OF THE TOTAL ENVIRONMENT".2024 May;9 5. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222 4. [IF=6] Honglin Liu et al."Tanshinone IIA as a therapy for PCOS via FOS/JUN/TP53 axis: Evidence from network pharmacology of Bajitian-Danshen pair."Arabian Journal of Chemistry".2024 Feb;:105641 3. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284 2. [IF=7.5] Xiangke Ma et al."Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2."BIOMEDICINE & PHARMACOTHERAPY.10.1016/j.biopha.2023.115501 1. [IF=8.8] Baixi Shan et al."Tanshinone II ameliorates energy metabolism dysfunction of pulmonary fibrosis using 13C metabolic flux analysis."Journal of Pharmaceutical Analysis.10.1016/j.jpha.2023.09.008

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