50. [IF=12.9] Jianheng Ren, et al. "A modular design of two-pronged sub-organelle targeting strategy disrupting mitochondria-endoplasmic reticulum crosstalk for mitigating rheumatoid arthritis"BIOMATERIALS, 2026 Oct;333:124212 49. [IF=8.2] Wenying Zhang et al."Biomimetic Liposome Coloaded ES-Cu and PFK15 Amplify Cuproptosis through Inhibition of Glycolysis in Fibroblast-Like Synoviocytes for Rheumatoid Arthritis Therapy."ACS Applied Materials & Interfaces 48. [IF=10.2] Jing Li et al."Non-antibiotic lipid complex-in-thermogel strikes twice: multimodal photosensitive antibacterial meets immunomodulation-boosted healing for periodontitis treatment."Materials Today Bio.2026 Jan;:102781 47. [IF=11.9] Mengting Liu et al."Hypoxia-responsive hybrid nanoparticles loaded with fingolimod and colistin against multidrug-resistant Klebsiella pneumoniae with mature biofilm."Asian Journal of Pharmaceutical Sciences.2025 Nov;:101107 46. [IF=12.6] Lan Jinshuai et al."Astragalus polysaccharide-based nano-platforms loading PTX to boost chemo-immunotherapy for triple-negative breast cancer with intrinsic GLUT-targeting ability and immunoregulatory activity."JOURNAL OF NANOBIOTECHNOLOGY.2025 Dec;23(1): 45. [IF=19] Xinyue Shao et al."Inhibiting NFS1 by Targeting Liposomes for Combating Cisplatin-Resistant Colorectal Cancer."ADVANCED FUNCTIONAL MATERIALS.2025 Oct;:e19005 44. [IF=8.5] Henglai Sun et al."Preparation and evaluation of anti-hepatocellular carcinoma activity of oridonin nanoparticles using Angelica sinensis polysaccharide and ursodeoxycholic acid as carrier."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2025 Sep;:1474 43. [IF=11.5] Hongxin Tan et al."Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy."JOURNAL OF CONTROLLED RELEASE.2025 Nov;387:114242 42. [IF=12.6] Gan Jingjing et al."Separable cryo-microneedle patches delivery with capsaicin integrated mesoporous dopamine for obesity treatment."JOURNAL OF NANOBIOTECHNOLOGY.2025 Dec;23(1):1-16 41. [IF=16] Lifeng Liu et al."Reprogramming Macrophage via an Antigen Phagocytosis-Presentation Nanoenhancer for Improved Cancer Immunotherapy."ACS Nano.2025;19(34):31077–31091 40. [IF=16] Lifeng Liu et al."Reprogramming Macrophage via an Antigen Phagocytosis-Presentation Nanoenhancer for Improved Cancer Immunotherapy."ACS Nano.2025;19(34):31077–31091 39. [IF=6.5] Jie Zhou et al."RGD-Functionalized Ginsenoside Rg3 Liposomes for Alleviating Oxidative Stress and Choroidal Neovascularization in Age-Related Macular Degeneration."International Journal of Nanomedicine. 38. [IF=10.6] Li Yong et al."Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage."JOURNAL OF NANOBIOTECHNOLOGY.2024 Dec;22(1):1-18 37. [IF=4.9] Jingwen Yang et al."Cell Membrane Hybrid Liposome-Targeted Delivery of the Heat Shock Protein 90 C-Terminal Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis."ACS Pharmacology & Translational Science.2024;XXXX(XXX):XXX-XXX 36. [IF=9.4] Lixuan Yin et al."A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy."Acta Biomaterialia.2024 Dec;: 35. [IF=4.2] Siqi Li et al."Glutathione-responsive polypeptide nanogel encapsulates Shikonin for breast cancer therapy."Nanomedicine-Nanotechnology Biology and Medicine.2025 Feb;64:102802 34. [IF=9.4] Yizhen Jia et al."Enhanced nasal-to-brain drug delivery by multivalent bioadhesive nanoparticle clusters for cerebral ischemic reperfusion injury protection."Acta Biomaterialia.2025 Jan;: 33. [IF=8.7] Hongmei Zhang et al."Targeting Capture and Eradicate Circulating Tumor Cells by Activated Platelet derived vehicle for inhibiting Triple-Negative Breast Cancer Metastasis."Materials Today Bio.2025 Feb;:101597 32. [IF=7.7] Shuang Cai et al."Rhein-loaded chitosan nanoparticles for treatment of MRSA-infected wound."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Nov;279:135360 31. [IF=3.7] Anqi Wang et al."Targeting Inflammatory Lesions Facilitated by Galactosylation Modified Delivery System Eudragit/Gal-PLGA@Honokiol for the treatment of Ulcerative Colitis."JOURNAL OF PHARMACEUTICAL SCIENCES.2024 Jun;: 30. [IF=6.7] Huating Huang et al."Preparation and anti-tumor effect in Hepatocellular Carcinoma Treatment of AS1411 aptamer-targeted Polyphyllin II-loaded PLGA nanoparticles."Journal of Science-Advanced Materials and Devices.2024 Jun;:100755 29. [IF=7.7] Xin Lin et al."Alginate nanogel-embedded liposomal drug carriers facilitate drug delivery efficiency in arthritis treatment."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Jul;273:133065 28. [IF=10.2] Xilong Cui et al."Charge Adaptive Phytochemical-based Nanoparticles for Eradication of Methicillin-Resistant Staphylococcus aureus Biofilms."Asian Journal of Pharmaceutical Sciences".2024 Apr;:100923 27. [IF=18.9] Jian Li et al."ROS-responsive & scavenging NO nanomedicine for vascular diseases treatment by inhibiting endoplasmic reticulum stress and improving NO bioavailability."Bioactive Materials".2024 Jul;37:239 26. [IF=4.6] Henglai Sun et al."Angelica Sinensis Polysaccharide-Based Nanoparticles for Liver-Targeted Delivery of Oridonin."MOLECULES".2024 Jan;29(3):731 25. [IF=5.9] Yangjia Li et al."Constructing Dendrobium officinale extracts-coated zein nanoparticles as oral delivery vehicles for curcumin."INDUSTRIAL CROPS AND PRODUCTS".2024 May;211:118229 24. [IF=8.2] Xi Yin et al."Precision targeting of CuET overload to disrupt mitochondrial unfolded protein response by integrated liposome."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 Mar;262:129974 23. [IF=5.5] Yong Li et al."Self-Assembled nanoparticles of natural bioactive molecules enhance the delivery and efficacy of paclitaxel in glioblastoma."CNS Neuroscience & Therapeutics.2023 Dec;: 22. [IF=3.3] Zhang Xueyan et al."A (Traditional Chinese Medicine) TCM-Inspired Doxorubicin Resistance Reversing Strategy: Preparation, Characterization, and Application of a Co-loaded pH-Sensitive Liposome."AAPS PHARMSCITECH.10.1208/s12249-023-02630-8 21. [IF=5.4] Zhu Shunyao et al."Combined immunochemotherapy achieving targeted co-delivery of chlorogenic acid and doxorubicin by sialic acid-modified liposomes enhances anti-cancer efficacy."Drug Delivery and Translational Research.10.1007/s13346-023-01426-4 20. [IF=5.8] Fangqian Sui et al."pH-triggered “PEG” sheddable and folic acid-targeted nanoparticles for docetaxel delivery in breast cancer treatment."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Sep;644:123293 19. [IF=4.6] Xiaojie Wang et al."Study of Salidroside and Its Inflammation Targeting Emulsion Gel for Wound Repair."MOLECULES.2023 Jan;28(13):5151 18. [IF=9.273] Jia Zeng et al."Bone Mesenchymal Stem Cell-derived Exosomes Involved Co-delivery and Synergism Effect with Icariin via Mussel-inspired Multifunctional Hydrogel for Cartilage Protection."Asian Journal of Pharmaceutical Sciences.2023 Mar;:100799 17. [IF=19.924] Lili Qian et al."Wearable, Self-powered, Drug-Loaded Electronic Microneedles for Accelerated Tissue Repair of Inflammatory Skin Disorders."ADVANCED FUNCTIONAL MATERIALS.2023 Mar;:2209407 16. [IF=6.208] Longkun Wang et al."Transcytosable Peptide-Paclitaxel Prodrug Nanoparticle for Targeted Treatment of Triple-Negative Breast Cancer."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(5):4646 15. [IF=11.467] Wei Li et al."Co-delivery of microRNA-150 and quercetin by lipid nanoparticles (LNPs) for the targeted treatment of age-related macular degeneration (AMD)."JOURNAL OF CONTROLLED RELEASE.2023 Mar;355:358 14. [IF=4.927] Huanhuan Guo et al."Research and Application of Kupffer Cell Thresholds for BSA Nanoparticles."MOLECULES.2023 Jan;28(2):880 13. [IF=8.663] Lukuan Xie et al."Rhynchophylline-encapsulating core-shell nanoparticles to overcome blood-brain-barrier and inhibit drug efflux for efficient anti-Parkinson therapy."Applied Materials Today.2023 Feb;30:101715 12. [IF=4.432] Xiaojie Wang et al."Pharmacodynamics of Dracorhodin Perchlorate and Its Inflammation-Targeting Emulsion Gel for Wound Healing."Gels.2022 Nov;8(11):712 11. [IF=7.59] Jian Li et al."Targeted delivery of liver X receptor agonist to inhibit neointimal hyperplasia by differentially regulating cell behaviors."Biomaterials Science.2022 Aug;: 10. [IF=6.525] Huimin Wu et al."Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers."Pharmaceutics.2022 Jun;14(6):1277 9. [IF=5.268] Xuling Chen et al."A novel multifunctional nanoparticles formed by molecular recognition between AS1411 aptamer and redox-responsive paclitaxel-nucleoside analogue prodrug for combination treatment of β-lapachone and paclitaxel."Colloid Surface B. 2022 Ap 8. [IF=6.321] Yujie Zheng et al."Microemulsion Delivery System Improves Cellular Uptake of Genipin and Its Protective Effect against Aβ1-42-Induced PC12 Cell Cytotoxicity."Pharmaceutics. 2022 Mar;14(3):617 7. [IF=3.246] Yu Xuan et al."Preparation and Characterization of PLGA–PEG–PLGA Nanoparticles Containing Salidroside and Tamoxifen for Breast Cancer Therapy."Aaps Pharmscitech. 2020 Apr;21(3):1-11 6. [IF=3.981] Xinyan Liu et al."Combination of essential oil from Zanthoxylum bungeanum Maxim. and a microemulsion system: Permeation enhancement effect on drugs with different lipophilicity and its mechanism."J Drug Deliv Sci Tec. 2020 Feb;55:101309 5. [IF=4.192] Haibo Pan et al."Assembly of Oil-Based Microcapsules Coated with Proanthocyanidins as a Novel Carrier for Hydrophobic Active Compounds."J Agr Food Chem. 2020;68(20):5715–5722 4. [IF=6.183] Tiankuan Li et al."PD-L1-targeted microbubbles loaded with docetaxel produce a synergistic effect for the treatment of lung cancer under ultrasound irradiation."Biomater Sci-Uk. 2020 Mar;8(5):1418-1430 3. [IF=6.419] Xixi Li et al."Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects."Drug Deliv. 2021;28(1):1849-1860 2. [IF=10.435] Yang Meng et al."Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics."J Nanobiotechnol. 2017 Dec;15(1):1-15 1. Liu, Xinyan, et al. "Combination of essential oil from Zanthoxylum bungeanum Maxim. and a microemulsion system: Permeation enhancement effect on drugs with different lipophilicity and its mechanism." Journal of Drug Delivery Science and Technology 55 (2020