链脲佐菌素

140. [IF=4.1] Yunjiao Shen, et al. "Centella Asiatica Alleviates Type 2 Diabetes-Related Hepatic Glycolipid Disorders via Regulating UPP1-Mediated Pyrimidine Metabolism"CURRENT ISSUES IN MOLECULAR BIOLOGY, 2026 Jun;48(7):663 139. [IF=5] Yuhuan Zhang, et al. "Hydrophobic ion pairing formed semaglutide designed for oral self-microemulsifying delivery in diabetes treatment"EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2026 Sep;226:115167 138. [IF=5.6] Xiuqi Zou, et al. "Modified Huanglian Wendan Decoction improves prediabetic renal injury by activating the AMPK/ULK1 pathway to restore autophagy and suppress inflammation"INTERNATIONAL IMMUNOPHARMACOLOGY, 2026 Sep;185:116966 137. [IF=2.9] Shengguang Wu, et al. "Study on the Mechanism of Traditional Chinese Medicine Compound Shixiang Plaster Improving Diabetic Wound Healing through MAPK Regulation of Macrophage Polarization"BURNS, 2026 Feb;:107940 136. [IF=5.1] Xing Wang, et al. "Gentiopicroside alleviates type 2 diabetes mellitus by attenuating oxidative stress and reshaping gut microbiota in high-fat diet and streptozotocin-induced mice"Frontiers in Nutrition, 2026 Feb;13:1768857 135. [IF=6.3] Long Cheng, et al. "Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis"PHYTOTHERAPY RESEARCH, 2026 Feb;: 134. [IF=3.4] Li Zhao, et al. "Shenqi Dihuang Decoction Attenuates ALOX5‐Mediated Ferroptosis in Diabetic Nephropathy via AMPK/mTOR and TGF‐β/Smads Pathways"Journal of Diabetes Research, 2026 Mar;2026:2872977 133. [IF=3.5] Wenjuan Li, et al. "MR Elastography in Diabetic Rats: Assessing Glomerular Hyperfiltration, Dapagliflozin Therapy Response, and Early Diabetic Nephropathy"JOURNAL OF MAGNETIC RESONANCE IMAGING, 2026 Mar;: 132. [IF=6.2] Zhengwei Tan, et al. "Extracellular Polysaccharides of Eurotium cristatum from Fu Brick Tea Ameliorated Type 2 Diabetes in Mice by Remodeling of Gut Microbiota-Dependent Tryptophan Metabolism to Activate the Hepatic AhR/TSC2/mTORC1 Axis"JOURNAL OF AGRICUL 131. [IF=6.4] Yu Chen, et al. "Sorafenib nanoparticles coated with Eudragit RL for ocular drug delivery: a potential treatment for diabetic retinopathy"International Journal of Pharmaceutics-X, 2026 Jun;11:100523 130. [IF=6.8] Jiahui Zhou, et al. "Discovery of Novel C-glycosyl Pyranose-Based Sulfonium and Selenonium Salts Targeting α-Glucosidase with Potent Antihyperglycemic Activity"JOURNAL OF MEDICINAL CHEMISTRY, 2026-03-09 129. [IF=6.5] Haoyang MIAO, et al. "Cyclodextrin–polysaccharide nanocomposite improves the oral stability and antidiabetic efficacy of chlorogenic acid in type 2 diabetic mice"Carbohydrate Polymer Technologies and Applications, 2026 Apr;:101137 128. [IF=2.2] Ting Pan et al."Tanshinone IIA Accelerates Diabetic Wound Healing via Suppression of Macrophage NLRP3 Inflammasome Activity."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2025 Dec;:153171 127. [IF=3.9] Sun Yaqin et al."Advanced glycation end products exacerbate lipopolysaccharide-induced acute lung injury with diabetes by promoting ferroptosis via AMP-activated protein kinase/acetyl-CoA carboxylase signaling."Scientific Reports.2025 Dec;15(1):43755 126. [IF=4.1] Lin Zhou et al."Cuscuta chinensis Lam. extracts ameliorate type 2 diabetes by regulating metabolism and gut microbiota."iScience.2026 Jan;29(1) 125. [IF=14.1] Rui Chen et al."Nanozyme-Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy."Advanced Science.2025 Dec;:e16389 124. [IF=4.2] Weidong Zhang et al."Rice Starch–Purple Red Rice Bran Anthocyanins Complex Improves Glucose–Lipid Homeostasis and Restores Gut Microbiota in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Mice."MOLECULAR NUTRITION & FOOD RESEARCH.2026 Jan;70(1):e703 123. [IF=5.4] Xian-Run Wu et al."Parameria laevigata (Juss.) Moldenke Healing Wound via PI3K/AKT/MAPK Pathway."JOURNAL OF ETHNOPHARMACOLOGY.2026 Jan;:121148 122. [IF=8.3] Anmei Shu et al."Breviscapine enhances angiogenesis in diabetic wound healing by regulating macrophage polarization via mitochondrial metabolic reprogramming."PHYTOMEDICINE.2026 Jan;:157794 121. [IF=4.3] Juntao Huang et al."Anti-diabetic effects of Dachaihu decoction combined with Sanghuangporus vaninii: insights from network pharmacology, intestinal flora, and liver metabolomics."Frontiers in Cell and Developmental Biology.2025 Nov;13:1707392 120. [IF=8.3] Qiang Chen et al."Eleutheroside B Liposomes Ameliorate Type 2 Diabetes Mellitus by Modulating Glucose and Lipid Metabolism: A Metabolomic Study."PHYTOMEDICINE.2025 Nov;:157628 119. [IF=8.5] Shiqi Xiao et al."Regulatory effects of polysaccharides from Houttuynia cordata Thunb. on gut microbiota and hyperglycemia in type 2 diabetes mellitus mice."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2026 Jan;335:149220 118. [IF=2.6] Yingnan Chen et al."Identification of oligopeptide components derived from Pseudostellaria heterophylla and its hypoglycemic effects in streptozotocin-induce type 2 diabetes mice."FITOTERAPIA.2025 Oct;:106919 117. [IF=12.5] Liying Ge et al."Nanozyme doped chitosan hydrogel driven by glucose oxidase for dual regulation of ROS homeostasis and macrophage reprogramming in diabetic wound healing."CARBOHYDRATE POLYMERS.2025 Oct;:124534 116. [IF=2.6] Guangyao Li et al."Mechanistic analysis of Inonotus hispidus in ameliorating T2DM: Metabolomics and gut microbiota profiling in mice models."FITOTERAPIA.2025 Sep;:106910 115. [IF=3] Xin Jin et al."Resina Draconis Promotes Diabetic Wound Healing by Regulating the AGE-RAGE Pathway to Modulate Macrophage Polarization."CURRENT ISSUES IN MOLECULAR BIOLOGY.2025 Sep;47(9):748 114. [IF=6.1] Min Cui et al."Empagliflozin Attenuates Diabetic Cardiomyopathy via Inhibiting Cardiomyocyte Ferroptosis Through the USP7/NRF2 Signaling Pathway."ANTIOXIDANTS & REDOX SIGNALING. 113. [IF=8.5] Wei Shen et al."Psyllium-derived, medium-molecular weight arabinoxylan enables modulation of the gut microbiota and metabolites in type 2 diabetic mice."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2025 Sep;:147363 112. [IF=12.5] Bozhang Xia et al."Site-specific adaptive nanovesicles for oral insulin delivery."Science Advances.2025 Sep;11(39) 111. [IF=4.9] Jianhong Liu et al."Piperine cocrystals ameliorates type 2 diabetes by regulating glycolipid metabolism and reshaping gut microbiota in mice."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2025 Nov;113:107356 110. [IF=4.9] Jianhong Liu et al."Piperine cocrystals ameliorates type 2 diabetes by regulating glycolipid metabolism and reshaping gut microbiota in mice."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2025 Nov;113:107356 109. [IF=3.9] Leping Ruan et al."Dual AMPK activation and TXNIP suppression underlie the superior anti-diabetic action of rosiglitazone-metformin co-crystal (RZM): evidence from preclinical models."JOURNAL OF DRUG TARGETING. 108. [IF=19] Shangpeng Liu et al."Iron Homeostasis Regulating Glycopeptide Hydrogel Reprograms the Healing Process of Diabetic Wounds Infected With MRSA."ADVANCED FUNCTIONAL MATERIALS.2025 Jun;:e09677 107. [IF=5.6] Ji Minrui et al."Dandelion-shaped strontium-gallium microparticles for the hierarchical stimulation and comprehensive regulation of wound healing."Regenerative Biomaterials.2024 Oct;: 106. [IF=7.7] Hao Hao et al."Enzyme-mediated multifunctional self-healing lysozyme hydrogel for synergistic treatment of chronic diabetic wounds."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Dec;282:136719 105. [IF=6.7] Jiarun Xie et al."Jia Wei Qingxin Lotus Seed Drink ameliorates epithelial mesenchymal transition injury in diabetic kidney disease via inhibition of JMJD1C/SP1/ZEB1 signaling pathway."PHYTOMEDICINE.2024 Oct;:156142 104. [IF=6.7] Junhao Huang et al."The volatile oil of Acorus tatarinowii Schott ameliorates Alzheimer's disease through improving insulin resistance via activating the PI3K/AKT pathway."PHYTOMEDICINE.2024 Oct;:156168 103. [IF=4.8] Jia-Lin Yu et al."Relationship Between Metabolomics of T2DM Patients and the Anti-Diabetic Effects of Phellodendri Chinensis Cortex-Anemarrhenae Rhizoma Herb Pair in Mice."JOURNAL OF ETHNOPHARMACOLOGY.2024 Nov;:119129 102. [IF=8.5] Minghao Yuan et al."Ursodeoxycholic acid grafted chitosan oligosaccharide self-assembled micelles with enhanced oral absorption and antidiabetic effect of oleanolic acid."FOOD CHEMISTRY.2024 Dec;:142708 101. [IF=3.8] Xingliang Xiang et al."Exploration of the mechanism of fermented turmeric preventing glucolipid metabolic disorder: Insights into signaling of microbiota-SCFAs-brown adipose tissue axis in mice."Journal of Functional Foods.2025 Feb;125:106675 100. [IF=7.7] Yujie Yang et al."A water-soluble polysaccharide from finger citron ameliorates diabetes mellitus via gut microbiota-GLP-1 pathway in high-fat diet and streptozotocin-induced diabetic mice."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2025 Jan;:1401 99. [IF=4.8] Menglong Zhao et al."CXCL12 as a Potential Hub Gene for N-Acetylcysteine Treatment of T1DM Liver Disease."Biomolecules.2025 Feb;15(2):176 98. [IF=5.3] Shiqi Wu et al."H2S/Curcumin Coreleasing Biomineralized Zinc Sulfide Nanostructures for Diabetic Wound Healing."ACS Applied Nano Materials.2025;XXXX(XXX):XXX-XXX 97. [IF=1.3] Mei-Juan Liu et al."Xiexin Tang restores gut barrier function by regulating the differentiation of CD4+ T cells via GPRs and HDACs in T2DM rats."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 96. [IF=3.8] Meixian Ruan et al."Study on the active ingredients and molecular mechanisms of Polygonatum sibiricum beverage in the intervention of type 2 diabetes mellitus based on UPLC-MS, network pharmacology and experimental validation."Journal of Functional Foods. 95. [IF=4.8] Yanli Wang et al."Deciphering the effect of soluble dietary fiber from broccoli stem and leaf on metabolic syndrome and its hypoglycemic mechanism in diabetes mellitus."Food Bioscience.2025 Apr;:106546 94. [IF=4.8] Shi-Shi Qin et al."Alstonia scholaris (L.) R. Br. ameliorated diabetic nephropathy through PPAR-δ pathway."JOURNAL OF ETHNOPHARMACOLOGY.2025 May;348:119839 93. [IF=4.4] Haoxiang Sun et al."Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway."Frontiers in Pharmacology.2025 Apr;16: 92. [IF=4.8] Hui Zhang et al."Ginsenoside Rg1 attenuates T2DM-induced renal damage and fibrosis by inhibiting TRPC6-ChREBP-TXNIP signaling."JOURNAL OF ETHNOPHARMACOLOGY.2025 May;348:119863 91. [IF=7.7] Weiyan Yuan et al."Hyaluronic acid methacryloyl/chitosan methacryloyl/3-methacrylamidophenylboronic acid multifunctional hydrogel loading exosome for diabetic wound healing."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Sep;:135562 90. [IF=12.3] Zhang Jianhong et al."Body-worn and self-powered flexible optoelectronic device for metronomic photodynamic therapy."npj Flexible Electronics.2024 Sep;8(1):1-14 89. [IF=7.7] Shuang Liu et al."Hypoglycemic effect of orally administered resistant dextrins prepared with different acids on type 2 diabetes mice induced by high-fat diet and streptozotocin."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Oct;277:134085 88. [IF=2.9] Xinting Zhang et al."Insulin combined with N-acetylcysteine attenuates type 1 diabetes-induced splenic inflammatory injury in canines by inhibiting the MAPKs-NF-κB signaling pathway and pyroptosis."JOURNAL OF DIABETES AND ITS COMPLICATIONS.2024 Jul;:10880 87. [IF=2.6] Yukun Liu et al."Unravelling the hypoglycemic mechanism of Fuzhuan brick tea: insights into intestinal microbiota and metabolites in type 2 diabetes mellitus mice."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY.2024 Jun;: 86. [IF=5.1] Yujia Ou et al."Porphyra haitanensis glycoprotein regulates glucose homeostasis: targeting the liver."Food & Function.2024 Jun;: 85. [IF=6.9] Yinhui Mao et al."Isorhamnetin improves diabetes-induced erectile dysfunction in rats through activation of the PI3K/AKT/eNOS signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2024 Aug;177:116987 84. [IF=13.3] Youjun Ding et al."Natural multi-actives composited hydrogel patches for diabetic wound healing."CHEMICAL ENGINEERING JOURNAL.2024 Sep;495:153335 83. [IF=5.6] Yang Yu et al."Characterization and evaluation of the in vitro and in vivo anti-diabetic activities of camel milk protein hydrolysates derived with different protease digestions."Journal of Functional Foods".2024 Jun;117:106227 82. [IF=8.6] Meiling Su et al."Sustainable deep eutectic solvents induced the polymorph selectivity and high purification efficiency."SEPARATION AND PURIFICATION TECHNOLOGY".2024 Dec;349:127856 81. [IF=9.7] Guangli Xiang et al."A Zn-MOF-GOx-based Cascade Nanoreactor Promotes Diabetic Infected Wound Healing by NO Release and Microenvironment Regulation."Acta Biomaterialia".2024 May;: 80. [IF=1.4] Weijing Fan et al."Effect of total astragalosides on diabetic non-healing wound by regulating immune microenvironment."Postepy Dermatologii i Alergologii".2024 Mar;41(1): 79. [IF=5] Xingliang Xiang et al."Exploration of the hypoglycemic mechanism of Fuzhuan brick tea based on integrating global metabolomics and network pharmacology analysis."Frontiers in Molecular Biosciences.2023; 10: 1266156 78. [IF=1.6] Chen Xiaoyu et al."Faecal Untargeted Metabolomics Analysis Elucidates the Antihyperglycaemic Effect of Surfactin in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Mice."Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy.2023 Dec;: 77. [IF=5.6] Yan Lei et al."Elucidating the pharmacodynamic mechanisms of Yuquan pill in T2DM rats through comprehensive multi-omics analyses."Frontiers in Pharmacology.2023; 14: 1282077 76. [IF=6.1] Xiangnan Zhang et al."Effects of Fu brick tea polysaccharides on gut microbiota and fecal metabolites of HFD/STZ-induced type 2 diabetes rats."Food & Function.2023 Nov;: 75. [IF=7] Ma Zhouji et al."PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway."Cell Death Discovery.2023 Nov;9(1):1-15 74. [IF=4.1] Xijie Zhou et al."The bone mesenchymal stem cell-derived exosomal miR-146a-5p promotes diabetic wound healing in mice via macrophage M1/M2 polarization."MOLECULAR AND CELLULAR ENDOCRINOLOGY.2023 Oct;:112089 73. [IF=2.7] Shuanji Ou et al."Tibial cortex transverse transport potentiates diabetic wound healing via activation of SDF-1/CXCR4 signaling."PeerJ.10.7717/peerj.15894 72. [IF=4.8] Zhouji Ma et al."PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression."FASEB JOURNAL.10.1096/fj.202300874RR 71. [IF=5.1] Ligen Chen et al."Hyperglycemia symptom amelioration by Ascophyllum nodosum polysaccharides in mice with type 2 diabetes."Algal Research-Biomass Biofuels and Bioproducts.10.1016/j.algal.2023.103278 70. [IF=5.8] Jingyu He et al."Guard against internal and external: An antibacterial, anti-inflammation and healing-promoting spray gel based on lyotropic liquid crystals for the treatment of diabetic wound."INTERNATIONAL JOURNAL OF PHARMACEUTICS.10.1016/j.ijpharm.2023. 69. [IF=3.222] Pengmin Ji et al."Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice."RENAL FAILURE.2023;45(1):Article: 2197075 68. [IF=4.996] Li Na et al."Network pharmacology mechanism of Scutellarin to inhibit RGC pyroptosis in diabetic retinopathy."Scientific Reports.2023 Apr;13(1):1-15 67. [IF=3.2] Han Qingyue et al."Hippocampal transcriptome analysis reveals mechanisms of cognitive impairment in beagle dogs with type 1 diabetes."JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY.2023 Aug;: 66. [IF=3.6] Su Wu et al."Antidiabetic activity of eupafolin through peroxisome proliferator-activated receptor-gamma and PI3K/Akt signaling in Type 2 diabetic rats."JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY.2023 Aug;:e23463 65. [IF=4.3] Jin Qingsong et al."PIAS1 impedes vascular endothelial injury and atherosclerotic plaque formation in diabetes by blocking the RUNX3/TSP-1 axis."Human Cell.2023 Aug;:1-13 64. [IF=6.1] Yujia Ou et al."Gut microbiome-serum metabolism profiles insight into the hypoglycemic effect of Porphyra haitanensis glycoprotein on hyperglycemic mice."Food & Function.2023 Aug;: 63. [IF=7.9] Yinhui Mao et al."Combining transcriptomic analysis and network pharmacology to explore the mechanism by which Shaofu Zhuyu decoction improves diabetes mellitus erectile dysfunction."PHYTOMEDICINE.2023 Oct;119:155006 62. [IF=11.2] Suya Deng et al."Chitosan/silk fibroin nanofibers-based hierarchical sponges via a HClO self-producing cascade catalytic reaction accelerating infected diabetic wound healing."CARBOHYDRATE POLYMERS.2023 Aug;:121340 61. [IF=7.8] Jianjia Huang et al."N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-α-mediated apoptotic pathways and affecting linear ubiquitination."Translational Research.2023 Jul;: 60. [IF=19.924] Hao Xia et al."Glycopeptide-Based Multifunctional Hydrogels Promote Diabetic Wound Healing through pH Regulation of Microenvironment."ADVANCED FUNCTIONAL MATERIALS.2023 Apr;:2215116 59. [IF=6.376] Bai Tao et al."The promotion action of AURKA on post-ischemic angiogenesis in diabetes-related limb ischemia."MOLECULAR MEDICINE.2023 Dec;29(1):1-21 58. [IF=6.317] Yunfeng Zhao et al."Onchidium struma polysaccharides exhibit hypoglycemic activity and modulate the gut microbiota in mice with type 2 diabetes mellitus."Food & Function.2023 Jan;: 57. [IF=8.025] Zerun Li et al."Interactions between structure and function of resistant glucans for alleviating type 2 diabetes mellitus (T2DM) and its complications in mice."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Mar;231:123405 56. [IF=4.026] Lu, Wenjie et al."Metformin Hydrochloride Mucosal Nanoparticles-Based Enteric Capsule for Prolonged Intestinal Residence Time, Improved Bioavailability, and Hypoglycemic Effect."AAPS PHARMSCITECH.2023 Jan;24(1):1-14 55. [IF=8.025] Gang Xiang et al."Antioxidant and hypoglycemic activity of tea polysaccharides with different degrees of fermentation."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2022 Dec;: 54. [IF=5.195] Yuli Han et al."Ginsenoside Rg1 attenuates glomerular fibrosis by inhibiting CD36/TRPC6/NFAT2 signaling in type 2 diabetes mellitus mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115923 53. [IF=6.317] Zirui Huang et al."Sanghuangporus vaninii mixture ameliorated type 2 diabetes mellitus and altered intestinal microbiota in mice."Food & Function.2022 Oct;: 52. [IF=5.223] Zimu Zhang et al."Intestinal microbiology and metabolomics of streptozotocin-induced type 2 diabetes mice by polysaccharide from Cardamine violifolia."Journal of Functional Foods.2022 Oct;97:105251 51. [IF=3.246] Qingyue Han et al."Repeated Low-Dose Streptozotocin and Alloxan Induced Long-Term and Stable Type 1 Diabetes Model in Beagle Dogs."Biomed Research International.2022 Aug 08;2022:5422287 50. [IF=3.842] Qin Tingyu et al."Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy."MOLECULAR AND CELLULAR BIOCHEMISTRY.2022 Aug;:1-10 49. [IF=3.333] Junhao Huang et al."Shen Qi Wan Ameliorates Learning and Memory Impairment Induced by STZ in AD Rats through PI3K/AKT Pathway."Brain Sciences.2022 Jun;12(6):758 48. [IF=6.317] Mubai Sun et al."Black bean husk and black rice anthocyanin extracts modulated gut microbiota and serum metabolites for improvement in type 2 diabetic rats."Food & Function.2022 Jun;: 47. [IF=6.78] Min Liu et al."3,4-Dihydroxyphenylacetic acid ameliorates gut barrier dysfunction via regulation of MAPK-MLCK pathway in type 2 diabetes mice."LIFE SCIENCES.2022 Sep;305:120742 46. [IF=3.639] Min Liu et al."Peanut Skin Procyanidins Ameliorates Insulin resistance via Modulation of Gut Microbiota and Gut Barrier in Type 2 Diabetic Mice."JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 45. [IF=6.953] Lan Pang et al."Two glycoproteins from medicinal insect Periplaneta americana (L.) promote diabetic wound healing via macrophage polarization modulation."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2022 Jun;209:2130 44. [IF=6.953] Qian Liao et al."Characterization and diabetic wound healing benefits of protein-polysaccharide complexes isolated from an animal ethno-medicine Periplaneta americana L.."Int J Biol Macromol. 2022 Jan;195:466 43. [IF=9.381] Yuanping Hao et al."Carboxymethyl chitosan-based hydrogels containing fibroblast growth factors for triggering diabetic wound healing."Carbohyd Polym. 2022 Jul;287:119336 42. [IF=6.843] Shilu Ji et al."An oxygen-sensitive probe and a hydrogel for optical imaging and photodynamic antimicrobial chemotherapy of chronic wounds."Biomater Sci-Uk. 2022 Apr;10(8):2054-2061 41. [IF=1.779] Shan-Na Chen et al."Protective effect of LIF-huMSCs on the retina of diabetic model rats."Int J Ophthalmol-Chi. 2021; 14(10): 1508–1517 40. [IF=2.952] Yunfeng Zhu et al."Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy."Mol Med Rep. 2021 Jun;23(6):1-12 39. [IF=4.219] Zhenlong Qin et al."Analysis of the analgesic effects of tricyclic antidepressants on neuropathic pain, diabetic neuropathic pain, and fibromyalgia in rat models."Saudi J Biol Sci. 2020 Sep;27:2485 38. [IF=4.545] Zhongyuan Wang et al."Protective effects of AS-IV on diabetic cardiomyopathy by improving myocardial lipid metabolism in rat models of T2DM."Biomed Pharmacother. 2020 Jul;127:110081 37. [IF=5.037] Mengyuan Fang et al."Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization."Life Sci. 2021 Jul;277:119567 36. [IF=5.396] Yue Ding et al."Combination of honey with metformin enhances glucose metabolism and ameliorates hepatic and nephritic dysfunction in STZ-induced diabetic mice."Food Funct. 2019 Nov;10(11):7576-7587 35. [IF=5.396] Jun-ping Liu et al."Antidiabetic activities of glycoprotein from pea (Pisum sativum L.) in STZ-induced diabetic mice."Food Funct. 2021 Jun;12(11):5087-5095 34. [IF=5.396] Xiaopeng Li et al."Diabetes diminishes a typical metabolite of litchi pericarp oligomeric procyanidins (LPOPC) in urine mediated by imbalanced gut microbiota."Food Funct. 2021 Jun;12(12):5375-5386 33. [IF=1.902] Yukun Feng et al."Validated LC-MS method for simultaneous quantitation of catalpol and harpagide in rat plasma: application to a comparative pharmacokinetic study in normal and diabetic rats after oral administration of Zeng-Ye-Decoction."Biomed Chromatog 32. [IF=3.701] Xiaopeng Li et al."A-type procyanidins from litchi pericarp ameliorate hyperglycaemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet."J Funct Foods. 2016 Dec;27:711 31. [IF=4.192] Xiaopeng Li et al."Attenuated mTOR Signaling and Enhanced Glucose Homeostasis by Dietary Supplementation with Lotus Seedpod Oligomeric Procyanidins in Streptozotocin (STZ)-Induced Diabetic Mice."J Agr Food Chem. 2017;65(19):3801–3810 30. [IF=4.451] Xiaopeng Li et al."Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice."J Funct Foods. 2018 May;44:155 29. [IF=5.396] Xiaopeng Li et al."(−)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice."Food Funct. 2018 Sep;9(9):4651-4663 28. [IF=6.529] Yinghui Ju et al."Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats."Biomed Pharmacother. 2019 Jan;109:84 27. [IF=6.953] Wei Xu et al."Anti-diabetic effects of polysaccharides from Talinum triangulare in streptozotocin (STZ)-induced type 2 diabetic male mice."Int J Biol Macromol. 2015 Jan;72:575 26. Li, Xiaopeng, et al. "Attenuated mTOR signaling and enhanced glucose homeostasis by dietary supplementation with lotus seedpod oligomeric procyanidins in streptozotocin (STZ)-induced diabetic mice." Journal of agricultural and food chemistry 65.19 (2017): 25. Li, Xiaopeng, et al. "A-type procyanidins from litchi pericarp ameliorate hyperglycaemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet." Journal of Functional Foods 27 (2016): 711-7 24. Ding, Yue, et al. "Combination of honey with metformin enhances glucose metabolism and ameliorates hepatic and nephritic dysfunction in STZ-induced diabetic mice." Food & function 10.11 (2019): 7576-7587.https://doi.org/10.1039/C9FO01575B 23. Jayachandran, Muthukumaran, Ramachandran Vinayagam, and Baojun Xu. "Guava leaves extract ameliorates STZ induced diabetes mellitus via activation of PI3K/AKT signaling in skeletal muscle of rats." Molecular biology reports 47.4 (2020): 2793-2799. 22. Wei Xu, Qing Zhou, Jiao-jiao Yin, Yong Yao, Jiu-liang Zhang, Anti-diabetic effects of polysaccharides from Talinum triangulare in streptozotocin (STZ)-induced type 2 diabetic male mice, International Journal of Biological Macromolecules, Volume 72, 2015, P 21. Jayachandran, Muthukumaran, et al. "Isoquercetin upregulates antioxidant genes, suppresses inflammatory cytokines and regulates AMPK pathway in streptozotocin-induced diabetic rats." Chemico-biological interactions 303 (2019): 62-69.https://doi.org/10.1016 20. Li, Xiaopeng, et al. "Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice." Journal of Functional Foods 44 (2018): 155-165.https://doi.org/1 19. 闫爽,李光耀,戴丛书,崔昊震,柳振宇,林长青.人参皂苷CK对2型糖尿病大鼠肝损伤的保护机制[J].食品工业科技,2021,42(02):310-315. 18. 随风,时昭红.胰高血糖样肽1对非酒精性脂肪肝大鼠CFHR1～5表达的影响[J].中国免疫学杂志,2021,37(01):36-40. 17. 季天娇. 黄芪甲苷调节PI3K/Akt通路来改善2型糖尿病大鼠肝糖代谢异常的分子机制[D].安徽医科大学,2020. 16. 马可可,鞠营辉,陈清青,李维祖,李卫平.黄芪甲苷对2型糖尿病肾病大鼠肾组织PI3K/Akt/FoxO1信号调控的影响[J].中国实验方剂学杂志,2019,25(02):74-81. 15. 李丽, 黄雪梦, 杨璐嘉,等. 采用2种降糖模型考察核桃蛋白及多肽的降糖作用[J]. 食品科技, 2017, 042(004):218-221. 14. 袁利佳,张蕾,张晓东.蝙蝠蛾拟青霉菌粉对糖尿病模型大鼠的保护作用[J].食用菌学报,2018,25(02):99-104+167. 13. 张哲滔,车念聪,郑亚琳,田甜,魏晓艺,刘晔.菖蒲郁金汤化裁方对2型糖尿病合并非酒精性脂肪肝大鼠SREBP-1c表达和胰岛素抵抗的影响[J].北京中医药,2019,38(01):17-20+97. 12. 王海生, 谢永财, 李长征,等. 石斛合剂对高脂高糖糖尿病大鼠心肌细胞Ca2+代谢的影响[J]. 福建中医药, 2020, 051(001):47-50. 11. 王航利, 张梦迪, 黄绳武. 益气补阴方对气阴两虚证糖尿病大鼠的降血糖作用研究[J]. 中药新药与临床药理, 2020(8). 10. 伏瑶,周继栋,桑晓宇,孙笛洋,赵启韬,傅风华.瓜蒌薤白半夏汤对2型糖尿病合并急性心肌缺血大鼠造血干细胞的保护作用机制[J].中华中医药杂志,2020,35(05):2613-2617. 9. 汤陈鹏, 吕峰, 刘伊娜. 孔石莼多糖锌对Ⅰ型糖尿病小鼠糖脂代谢及体内抗氧化的干预作用[J]. 食品工业科技, 2020, v.41;No.441(01):301-306+315. 8. 胡江, 缪菁, 段淑芳,等. 大黄酸对2型糖尿病模型大鼠的保护作用[J]. 中国药房, 2014, 025(023):2113-2116. 7. 杨文超, 顾正位, 路其康,等. 复方葛根片对糖尿病肾病模型大鼠肾组织的保护作用[J]. 中国药房, 2015(34). 6. 孙昕, 刘卫. 复方川芎滴丸对糖尿病肾病模型大鼠血液流变学及血气的影响[J]. 中国药房, 2017(7). 5. 崔祥,尚尔鑫,江曙,钱大玮,段金廒.基于响应曲面法对黄芩-黄连配伍改善2型糖尿病糖脂代谢紊乱的相互作用研究[J].药学学报,2018,53(04):630-635. 4. 张文锦 方朝晖 赵媛媛 等. 启元胶囊对糖尿病模型大鼠周围神经病变干预机制[J]. 中医药临床杂志 2019 v.31(11):120-123. 3. 吉艳梅 文彩铃.六味地黄丸联合胰岛素对妊娠糖尿病大鼠血清皮质酮及胎盘11β-羟基类固醇脱氢酶表达的影响[J].解放军药学学报 2018 34(03):221-224+253. 2. 周国佩 吴帆 朱金华 et al. 乌梅丸对2型糖尿病模型大鼠肠道菌群 炎性因子及短链脂肪酸的影响[J]. 中国实验方剂学杂志 2020(10). 1. 朱戈丽 伍军 张艳霞 等. miR-21介导PTEN/SMAD7信号传导通路调控糖尿病肾病大鼠肾纤维化作用研究[J]. 临床误诊误治 2020年33卷7期 104-108页 ISTIC 2020.