Name: 环磷酰胺，一水
Brand: 源叶生物
SKU: T92484
Availability: InStock

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

T92484-1ml

10mM in DMSO

￥205.00

>10

产品描述：

Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. It is also believed to possess immunosuppressive properties. Cyclophosphamide Monohydrate inhibits ALDH1 (aldehyde dehydrogenase 1) through its degradation product acrolein, as well as induces apoptosis in the rat thymus via the Fas/Fas ligand pathway.;Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. It is also believed to possess immunosuppressive properties. Cyclophosphamide Monohydrate inhibits ALDH1 (aldehyde dehydrogenase 1) through its degradation product acrolein, as well as induces apoptosis in the rat thymus via the Fas/Fas ligand pathway.An immunosuppressive, cytotoxic apoptosis inducer.

体内研究：

注意：
请勿仅参考一篇文章来确定实验条件。建议在正式实验前，通过预实验确定最佳实验条件 (动物品系、年龄、剂量、频率及周期、检测时间及指标等)。

Cyclophosphamide (腹腔注射；2 mg/小鼠，溶于 0.1 mL PBS，在携带 SW1 肿瘤的 C3H 小鼠中) 增加了脾脏和肿瘤中染色为 CD3、CD4 或 CD8 的细胞比例。

溶解性：

10mg/ml 水（溶液状态不稳定，需要现配现用）。

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.583 ml	17.915 ml	35.829 ml
5 mM	0.717 ml	3.583 ml	7.166 ml
10 mM	0.358 ml	1.791 ml	3.583 ml
50 mM	0.072 ml	0.358 ml	0.717 ml